N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE)
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N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) ??
- ???
- 118-120 °C
- ?? ?
- 530℃
- ??
- 0.726
- ???
- 1.6200 (estimate)
- ???
- 275℃
- ?? ??
- Inert atmosphere,2-8°C
- ???
- ???(?? ??), DMSO(?? ???), ???(?? ???, ??, ??? ??)
- ?? ?? (pKa)
- 12.28±0.46(Predicted)
- ??? ??
- ??
- ??? ??
- ??? ??
- ??
- ???? ?????
- InChI
- 1S/C12H20Cl4N2O2/c13-9(14)11(19)17-7-5-3-1-2-4-6-8-18-12(20)10(15)16/h9-10H,1-8H2,(H,17,19)(H,18,20)
- InChIKey
- FAOMZVDZARKPFJ-UHFFFAOYSA-N
- SMILES
- O=C(NCCCCCCCCNC(C(Cl)Cl)=O)C(Cl)Cl
- CAS ??????
- 1477-57-2
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn | ||
|---|---|---|---|
| ?? ???? ?? | 20/21/22-40 | ||
| ????? | 24/25-45-36 | ||
| WGK ?? | WGK 3 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Carc. 2 |
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| ?? | LD50 orally in mice: >16000 mg/kg (Coulston) |
N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) C??? ??, ??, ??
??? ??
white crystalline powder??
Win 18446 was shown to inhibit the biosynthesis of retinoic acid from retinol in neonatal and adult murine testis and in the embryonic murine gonad.??
ChEBI: A carboxamide that is 1,8-diaminooctane in which a hydrogen attached to each of the amino groups has been replaced by a dichloroacetyl group. Inhibitor of aldehyde dehydrogenase 1a2 (ALDH1a2). Inhibits the biosynthesis of retinoic acid from retinol in neon tal and adult murine testis. It down-regulates sex related genes in zebrafish.Safety Profile
Poison by intraperitoneal route.Human systemic effects by ingestion: nausea andvomiting. Human reproductive effects by ingestion:changes in spermatogenesis. An experimental teratogen.Other experimental reproductive effects. Human mutationdata reporteN,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) ?? ?? ? ???
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N,N'-OCTAMETHYLENEBIS(DICHLOROACETAMIDE) ?? ??
???( 111)?? ??
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