BESTATIN HYDROCHLORIDE
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BESTATIN HYDROCHLORIDE ??
- ???
- 216-218 °C
- ?? ??
- 2-8°C
- ???
- H2O: 25 mg/mL, ??, ??
- ??? ??
- ?? ?? ??? ??.
- ??
- ???
- ???? ??
- synthetic (organic)
- ???
- ?(4 mg/ml, ???), DMSO(>25 mg/ml), ???, ????, ??? ????? ? 100% ???? ?????.
- BRN
- 4628066
- ???
- ?? 1?? ?? -20°?? DMSO, ??? ?? ???? ??????.
- InChI
- 1S/C16H24N2O4.ClH/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11;/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22);1H/t12-,13+,14+;/m1./s1
- InChIKey
- XGDFITZJGKUSDK-UDYGKFQRSA-N
- SMILES
- O=C(N[C@@H](CC(C)C)C(O)=O)[C@@H](O)[C@H](N)CC1=CC=CC=C1.Cl[H]
- CAS ??????
- 65391-42-6(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn | ||
|---|---|---|---|
| ?? ???? ?? | 20/21/22-36/37/38 | ||
| ????? | 22-24/25-36-26 | ||
| WGK ?? | 3 | ||
| F ?????? | 3-10 | ||
| HS ?? | 29242995 | ||
| ???? ??? | 11 - Combustible Solids |
| ????(GHS): |
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BESTATIN HYDROCHLORIDE C??? ??, ??, ??
??
competitive aminopeptidase B inhibitor?? ??
Chemical structure: amino acid derivativesBiochem/physiol Actions
A metalloprotease inhibitor selective for aminopeptidase. Bestatin is a competitive and specific inhibitor of leucine aminopeptidase, aminopeptidase B, and triamino peptidase. It inhibits aminopeptidase B at 60 nM (using arginine-β-naphthylamide as substrate) and leucine aminopeptidase at 20 nM (leucine-β-naphthylamide as substrate). It showed no inhibition of aminopeptidase A, trypsin, chymotrypsin, elastase, papain, pepsin, or themolysin. It offers promise as a novel analgesic because it protects endogenous opioid peptides against degradation.BESTATIN HYDROCHLORIDE ?? ?? ? ???
???
?? ??
BESTATIN HYDROCHLORIDE ?? ??
???( 197)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hebei Zhuanglai Chemical Trading Co.,Ltd | 13343047651 |
admin@zlchemi.com | China | 3692 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29812 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 |
sale@chuangyingchem.com | CHINA | 5906 | 58 |
| CONIER CHEM AND PHARMA LIMITED | |
sales@conier.com | China | 49979 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +1-00000000000 |
marketing@targetmol.com | United States | 32468 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1059@dideu.com | China | 29119 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 |
gksales1@gk-bio.com | China | 9047 | 58 |
| BOC Sciences | 16314854226; +8616314854226 |
inquiry@bocsci.com | United States | 19853 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 |
sales@nextpeptide.com | China | 19908 | 58 |
| Nanjing Doge Biomedical Technology Co., Ltd | +86-25-58227606 +86-15305155328 |
sales@dogechemical.com | China | 4128 | 58 |
BESTATIN HYDROCHLORIDE ?? ??:
??? D-?????? ???????(1,3)
CARBOXYPEPTIDASE B
CARBOXYPEPTIDASE A
N-CARBOBENZOXY-DL-LEUCINE
Suc-Ala-Ala-Pro-Phe-SBzl
α-Chymotrypsin
Bestatin
N-(2-HYDROXYETHYL)LACTAMIDE
L-Leucine hydrochloride
DIETHANOLAMINE HYDROCHLORIDE
H-BETA-ALA-NH2 HCL
Betaine hydrochloride
BESTATIN HYDROCHLORIDE
(R)-(-)-4-PHENYL-2-BUTANOL
1,3-Diamino-2-propanol
N-ME-DL-LEU-OH HCL