Ethyl 6-chloronicotinate
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Ethyl 6-chloronicotinate ??
- ???
- 26-30 °C(lit.)
- ?? ?
- 98 °C
- ??
- 1.245±0.06 g/cm3(Predicted)
- ???
- 1.522
- ???
- >230 °F
- ?? ??
- Inert atmosphere,Room Temperature
- ???
- ?????(?? ???), ???(?? ???)
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- -1.95±0.10(Predicted)
- ??
- ??~??? ??
- BRN
- 4742175
- InChI
- 1S/C8H8ClNO2/c1-2-12-8(11)6-3-4-7(9)10-5-6/h3-5H,2H2,1H3
- InChIKey
- ILDJJTQWIZLGPO-UHFFFAOYSA-N
- SMILES
- CCOC(=O)c1ccc(Cl)nc1
- CAS ??????
- 49608-01-7(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38 | ||
| ????? | 26-36 | ||
| WGK ?? | 3 | ||
| ?? ?? | IRRITANT | ||
| HS ?? | 29339900 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 |
Ethyl 6-chloronicotinate C??? ??, ??, ??
??? ??
White to light yellow solid or colorless to yellow liquid??
Ethyl 6-chloronicotinate is a nicotinic acid derivative used in the preparation of potent H3 receptor antagonists.?? ??
Ethyl 6-chloropyridine-3-carboxylate (Ethyl-6-chloronicotinate, E-6-ClN) undergoes direct amidation on reacting with benzylamine in the presence lanthanum trifluoromethanesulfonate La(OTf)3. The structural and physicochemical properties of E-6-ClN have been investigated based on its spectroscopic data, time-dependent density functional theory and density of state diagrams.Ethyl 6-chloronicotinate ?? ?? ? ???
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Ethyl 6-chloronicotinate ?? ??
???( 308)?? ??
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