Terazosin
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Terazosin ??
- ???
- 281-283°C
- ?? ?
- 664.5±65.0 °C(Predicted)
- ??
- 1.332±0.06 g/cm3(Predicted)
- ?? ??
- -20°C Freezer
- ???
- H2O: 25 mg/mL
- ?? ?? (pKa)
- pKa (0.1N NaOH): 7.1(at 25℃)
- ??? ??
- ??
- ??
- ???? ?????
- ???
- 30.6mg/L(22.5℃)
- BCS Class
- 1/3
- InChIKey
- VCKUSRYTPJJLNI-UHFFFAOYSA-N
- CAS ??????
- 63590-64-7(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn,Xi | ||
|---|---|---|---|
| ?? ???? ?? | 22-36/37/38 | ||
| ????? | 26-36 | ||
| WGK ?? | 3 | ||
| RTECS ?? | TK8044925 |
| ????(GHS): |
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| ?? ?: | Warning | ||||||||||||||
| ??·?? ??: |
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| ??????: |
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Terazosin C??? ??, ??, ??
??? ??
White to Off-White Crystalline Powder??
Terazosin is used for the same indications as is prazosin; however, it has the advantage of being able to be used once a day.Synthesis
Terazosin, 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)- piperazine (12.2.13), only differs from prazosin in that the furyl radical is replaced with a tetrahydrofuryl radical. It is synthesized in exactly the same manner except using 1-(2-tetrahydrofuroyl)piperazine instead of 1-(2-furoyl)piperazine [48–51].Terazosin ?? ?? ? ???
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?? ??
Terazosin ?? ??
???( 166)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
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Terazosin ?? ??:
??????? ??? ???(???????)????? ????????? 1-????????? 6-??? ???? ????? 1,1-?????? ????????? ??? ??? ???? 3-?????
Piperacillin
TERAZOSIN RELATED COMPOUND B (50 MG) (1-(4-HYDROXY-6,7-DIMETHOXY-2-QUINAZOLINYL)-4-[(TETRA-HYDRO-2-FURANYL)CARBONYL]PIPERAZINE)
Terazosin hydrochloride dihydrate
Terazosin hydrochloride
TERAZOSIN RELATED COMPOUND C (25 MG) (1,4-BIS(4-AMINO-6,7-DIMETHOXY-2-QUINAZOLINYL)PIPER-AZINE DIHYDROCHLORIDE)
2-chloro-4-amino-6,7-dimethoxyquinazoline (intermediate of terazosin)
Quinazoline