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LCZ696???C

LCZ696???C
LCZ696???C ??? ???
?? ??:
149709-63-7
???:
LCZ696???C
???(??):
LCZ696???C
???:
LCZ 696 Impurity C
???(??):
Sacubitril S,S-Isomer;(2S,4S)-Sacubitril;LCZ 696 Impurity C;LCZ696 impuritiesC;Sacubitril Impurity C;Valsartan Impurity C-1;(2S,4S)-Sacubitril ,>=98%;valsartan/sacubitril Impurity 2;LCZ-696 Impurity 9 calcium salt;Sacubitril Impurity 45 Calciume
CBNumber:
CB23050352
???:
C24H29NO5
??? ??:
411.49
MOL ??:
149709-63-7.mol

LCZ696???C ??

?? ?
656.9±55.0 °C(Predicted)
??
1.151±0.06 g/cm3(Predicted)
?? ??
Hygroscopic, -20°C Freezer, Under inert atmosphere
???
?????(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
4.72±0.10(Predicted)
??
???? ?? ???
???
??? ???
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P330 ?? ?????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.

LCZ696???C C??? ??, ??, ??

??

(2S,4S)-Sacubitril is an impurity of Sacubitril (S080895) which is an antihypertensive drug used in combination with valsartan.

LCZ696???C ?? ?? ? ???

???

?? ??


LCZ696???C ?? ??

???( 73)?? ??
??? ?? ??? ?? ?? ? ??
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LCZ696???C ?? ??:

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