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Pyrimidine-5-boronic acid pinacol ester

Pyrimidine-5-boronic acid pinacol ester ??? ???
?? ??:
321724-19-0
???:
Pyrimidine-5-boronic acid pinacol ester
???(??):
AKOS BRN-1136;PYRIMIDYL-5-BORONIC ACID PINACOLATE;PYRIMIDINE-5-BORONIC ACID PINACOLATE;5-Pyrimidylboronic Acid Pinacol Ester;PYRIMIDYL-5-BORONIC ACID PINACOL ESTER;PYRIMIDINE-5-BORONIC ACID PINACOL ESTER;PYRIMIDIN-5-YLBORONIC ACID PINACOL ESTER;PINACOL ESTER PYRIMIDINYL-5-BORONIC ACID;5-Pyrimidineboronic acid pinacol ester;Pyrimidine-5-borate frequency which ester
CBNumber:
CB2380898
???:
C10H15BN2O2
??? ??:
206.05
MOL ??:
321724-19-0.mol

Pyrimidine-5-boronic acid pinacol ester ??

???
60-66°C
?? ?
308.9±15.0 °C(Predicted)
??
1.07±0.1 g/cm3(Predicted)
?? ??
under inert gas (nitrogen or Argon) at 2-8°C
??? ??
powder to crystal
?? ?? (pKa)
1.63±0.10(Predicted)
??
White to Orange to Green
CAS ??????
321724-19-0(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ?? IRRITANT
HS ?? 2933599590
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.
NFPA 704
0
2 0

Pyrimidine-5-boronic acid pinacol ester C??? ??, ??, ??

??

Pyrimidine-5-boronic acid pinacol ester is used in the preparation of indole derivatives as selective inhibitors of all three members of the Pim kinase family. It is also used to prepare inhibitors of TGF-β1 and activin A signalling.

Pyrimidine-5-boronic acid pinacol ester ?? ?? ? ???

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Pyrimidine-5-boronic acid pinacol ester ?? ??

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Pyrimidine-5-boronic acid pinacol ester ?? ??:

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