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dupilumab

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1190264-60-8
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dupilumab
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Dupliumab;REGN-668;dupilumab;SAR-231893;REGN-668|||SAR-231893;Dupilumab (anti-IL-4Ra);Research Grade Dupilumab;Research Grade Dupilumab(DHD62601)
CBNumber:
CB24919920
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0
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Mol file

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Dupilumab was first approved by the FDA in 2017 for atopic dermatitis. In the United States, subsequent approvals extended to include moderate-to-severe asthma in 2018, based on Phase III trials that confirmed improvements in lung function and reductions in exacerbation frequency. Further, Dupixent was approved for chronic rhinosinusitis with nasal polyposis (CRSwNP), an indication where inflammatory mediators play a key role in symptomatology. More recently, the FDA approved Dupixent for eosinophilic esophagitis in patients 12 years and older, representing a significant advance in managing this debilitating gastrointestinal disorder. Additionally, the drug received approval for prurigo nodularis, thereby expanding its portfolio of applications in chronic dermatological diseases characterized by intense pruritus.

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Dupilumab, also known as Dupixent, is a treatment for severe atopic eczema.

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