2-Hydroxy-N-(4-hydroxyphenyl)-benzamide
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2-Hydroxy-N-(4-hydroxyphenyl)-benzamide ??
- ???
- 179°
- ?? ?
- 371.13°C (rough estimate)
- ??
- 1.2084 (rough estimate)
- ???
- 0Pa at 25℃
- ???
- 1.5500 (estimate)
- ?? ??
- Sealed in dry,Room Temperature
- ???
- DMSO : ≥ 28 mg/mL (122.15 mM)
- ??? ??
- Solid
- ?? ?? (pKa)
- 8.40±0.30(Predicted)
- ??
- White to off-white
- ???
- 916mg/L at 25℃
- InChI
- 1S/C13H11NO3/c15-10-7-5-9(6-8-10)14-13(17)11-3-1-2-4-12(11)16/h1-8,15-16H,(H,14,17)
- InChIKey
- LGCMKPRGGJRYGM-UHFFFAOYSA-N
- SMILES
- N(c2ccc(cc2)O)C(=O)c1c(cccc1)O
- LogP
- 2.47 at 25℃
- CAS ??????
- 526-18-1(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn | ||
|---|---|---|---|
| ?? ???? ?? | 22-36/37/38-42/43 | ||
| ????? | 26-36/37 | ||
| WGK ?? | WGK 3 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Acute Tox. 4 Oral | ||
| ?? | LD50 oral in rat: 6702mg/kg |
| ????(GHS): |
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| ?? ?: | Warning | ||||||||||||||
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2-Hydroxy-N-(4-hydroxyphenyl)-benzamide C??? ??, ??, ??
Biochem/physiol Actions
Osalmid is a potent inhibitor of ribonucleotide reductase small subunit M2 (RRM2) that potently inhibits HBV DNA and cccDNA synthesis in HepG2.2.15 cells. Osalmid inhibits RR (ribonucleotide reductase) activity in vivo, and exhibits synergistic effect with lamivudine on inactivation mutant HBV strain. Osalmid is a biliation activator (choleretic agent), but a mechanism of this activity remains unknown.2-Hydroxy-N-(4-hydroxyphenyl)-benzamide ?? ?? ? ???
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2-Hydroxy-N-(4-hydroxyphenyl)-benzamide ?? ??
???( 159)?? ??
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2-Hydroxy-N-(4-hydroxyphenyl)-benzamide ?? ??:
???????? C.I. ?? ?? 5
N-(2-Hydroxynaphthoyl)-2,4-dimethoxy-5-chloroanilide
NAPHTHOL AS-LT
3-Hydroxy-4'-methoxy-2-naphthanilide
2-Hydroxy-N-(4-methoxyphenyl)-11H-benzo[a]carbazole-3-carboxamide
Rafoxanide
2-Hydroxy-N-(4-hydroxyphenyl)-benzamide
4'-ethoxysalicylanilide
4-hydroxy-N-(4-hydroxyphenyl)benzamide
4-hydroxy-N-(3-hydroxyphenyl)benzamide
3-hydroxy-N-(4-hydroxyphenyl)benzamide
AURORA 3537
N-(4-HYDROXYPHENYL)-2-METHOXYBENZAMIDE
AURORA 3538
AURORA 383
AURORA 2063
N,N-DIMETHYL(2-([4-(TRIFLUOROMETHOXY)ANILINO]CARBONYL)PHENYL)SULFAMATE