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?????? ??? ???
?? ??:
1088-92-2
???:
??????
???(??):
??????
???:
nifurtoinol
???(??):
urfadyn;Urfurine;nifurtoinol;3-(Hydroxymethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione;2,4-Imidazolidinedione, 3-(hydroxymethyl)-1-[[(5-nitro-2-furanyl)methylene]amino]-;3-(HYDROXYMETHYL)-1-[[(E)-(5-NITRO-2-FURYL)METHYLIDENE]AMINO]-2,4-IMIDAZOLIDINEDIONE;3-(hydroxymethyl)-1-[(E)-(5-nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione
CBNumber:
CB2876175
???:
C9H8N4O6
??? ??:
268.18
MOL ??:
1088-92-2.mol

?????? ??

???
258 °C (decomp)
?? ?
411.35°C (rough estimate)
??
1.5401 (rough estimate)
???
1.6590 (estimate)
?? ?? (pKa)
13.41±0.10(Predicted)
???
0.33g/L(22℃)

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ChEBI: An imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group and at position 3 by a hydroxymethyl group.

Pharmaceutical Applications

The hydroxymethyl derivative of nitrofurantoin, formulated for oral administration. The activity is similar to that of nitrofurantoin. Little is known about the pharmacokinetic behavior. It is said to be more rapidly absorbed than nitrofurantoin and excreted into the urine to a greater extent. Available in some countries in continental Europe.

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