ChemicalBook >?? ???? >?? ???>??? ?? ?? ???>?? ??>??? ?? ??>4-Aminopyrazolo[3,4-d]pyrimidine

4-Aminopyrazolo[3,4-d]pyrimidine

4-Aminopyrazolo[3,4-d]pyrimidine ??? ???

?? ??:: 2380-63-4

???:: 4-Aminopyrazolo[3,4-d]pyrimidine

???(??):: 1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-AMINE;4-app;4 APP;nsc1393;NSC 1393;4-Aminopyra;Aminopurinol;Pyrazoloadenine;TIMTEC-BB SBB004205;ADENINE ANTIMETABOLITE

CBNumber:: CB3112436

???:: C5H5N5

??? ??:: 135.13

MOL ??:: 2380-63-4.mol

MSDS

?? ?? 441

4-Aminopyrazolo[3,4-d]pyrimidine ??

???: >325 °C(lit.)

?? ?: 238.81°C (rough estimate)

??: 1.3795 (rough estimate)

???: 1.7000 (estimate)

?? ??: Keep in dark place,Inert atmosphere,Room temperature

???: DMSO? ???

??? ??: powder to crystal

?? ?? (pKa): 12.12±0.20(Predicted)

??: White to Orange to Green

???: ?? ???.

BRN: 5824

InChI: 1S/C5H5N5/c6-4-3-1-9-10-5(3)8-2-7-4/h1-2H,(H3,6,7,8,9,10)

InChIKey: LHCPRYRLDOSKHK-UHFFFAOYSA-N

SMILES: Nc1ncnc2[nH]ncc12

CAS ??????: 2380-63-4(CAS DataBase Reference)

NIST: 1H-pyrazolo[3,4-d]pyrimidin-4-amine(2380-63-4)

EPA: 1H-Pyrazolo[3,4-d]pyrimidin-4-amine (2380-63-4)

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	T
?? ???? ??	25-36/37/38-23/24/25
?????	26-36/37/39-45-22-36
????(UN No.)	UN 2811 6.1/PG 3
WGK ??	3
RTECS ??	UR0717000
TSCA	TSCA listed
?? ??	6.1
????	III
HS ??	29335990
???? ???	6.1D - Non-combustible acute toxic Cat.3 toxic hazardous materials or hazardous materials causing chronic effects
Hazard Classifications	Acute Tox. 3 Oral Eye Irrit. 2 Skin Irrit. 2 STOT SE 3
??	LD50 oral in rat: 141mg/kg

????(GHS):

?? ?:

Danger

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H301	??? ???	?? ?? ?? - ??	?? 3	??	P264, P270, P301+P310, P321, P330,P405, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P280	????/???/???/?????? ?????.
P301+P310	???? ?? ????(??)? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321	(…) ??? ???.
P405	???? ?????.
P501	...? ??? / ??? ?? ???.

NFPA 704

	0
3		0

4-Aminopyrazolo[3,4-d]pyrimidine MSDS

4-Aminopyrazolo[3,4-d]pyrimidine

4-Aminopyrazolo[3,4-d]pyrimidine C??? ??, ??, ??

??

4-aminopyrazolo[3,4-d]pyrimidine (4-APP), the isomer of adenine with the five-membered ring in the pyrazole configuration, is by far the most potent inhibitor of both enzymatic reactions catalyzed by Stx1. It is also a new type of mTOR inhibitor. The 4-aminopyrazolo[3,4-d]pyrimidines, a well-characterized class of compounds for tyrosine kinase inhibition, were used as a Src inhibitor module that blocks the adenosine binding site[1-2].

??? ??

Light Tan Solid

??

4-Amino-1H-pyrazolo[3,4-d]pyrimidine decreases serum cholesterol markedly in rats.

???

4-Aminopyrazolo[3,4-d]pyrimidine is harmful, irritating to the eyes and skin, and may cause respiratory irritation by inhalation. It is toxic if swallowed.

4-Aminopyrazolo[3,4-d]pyrimidine ?? ?? ? ???

???

formamide ????? ???? ???? 4-Chloro-1H-pyrazolo[3,4-d]pyrimidine 3-???-4-????????? ????? ?????????

?? ??

(3R)-1-Boc-3-(4-aMino-3-iodo-1H-pyrazolo[3,4-d]pyriMidin-1-yl)piperidine

4-Aminopyrazolo[3,4-d]pyrimidine ?? ??

???( 441)?? ??

???	??	???	??	?? ?	??
Changzhou uniringchem Co., Ltd.	+undefined13585446801	sales@uniringchem.com	China	69	58
OpChem(Changzhou) Co.,Ltd.	+undefined18112346326	info@op-chem.com	China	930	58
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ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60

4-Aminopyrazolo[3,4-d]pyrimidine ?? ??:

???????? ????? ??????? ?????? 3-??-1-??-2-????-5-? ?-2-?????? ??? Zolpidem tartrate 1H-PYRAZOL-4-YLAMINE 4-AMINOPYRAZOLO(3,4-D)PYRIMIDINE-6-OL Aminopyrazine Pyrazine 7-Aminopyrazolo[1,5-a]pyrimidine-3,6-dicarbonitrile 7-aminopyrazolo[1,5-a]pyrimidine-6-carbonitrile 7-aminopyrazolo(4,3-d)pyrimidine 1H-PYRAZOLO[3,4-D]PYRIMIDINE 4-Aminopyrazolo[3,4-d]pyrimidine 7-AMINOPYRAZOLO[1,5-A]PYRIMIDINE-3,6-DICARBOXYLIC ACID

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4-Aminopyrazolo[3,4-d]pyrimidine

4-Aminopyrazolo[3,4-d]pyrimidine ??

4-Aminopyrazolo[3,4-d]pyrimidine MSDS

4-Aminopyrazolo[3,4-d]pyrimidine C??? ??, ??, ??

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4-Aminopyrazolo[3,4-d]pyrimidine ?? ?? ? ???

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4-Aminopyrazolo[3,4-d]pyrimidine ?? ??

4-Aminopyrazolo[3,4-d]pyrimidine ?? ??: