panthenol (pro-vitamin B5) acts as a penetrating moisturizer. Panthenol appears to stimulate cellular proliferation and aid in tissue repair. Studies indicate that when topically applied, panthenol penetrates the skin and gets converted into pantothenic acid, a B complex vitamin. Such action could possibly influence the skin’s natural resources of pantothenic acid. It imparts a nonirritant, non-sensitizing, moisturizing, and conditioning feel and promotes normal keratinization and wound-healing. Panthenol protects the skin against sunburn, provides relief for existing sunburn, and enhances the natural tanning process. Panthenol’s humectant character enables it to hold water in the product or attract water from the environment, resulting in a moisturizing effect. It enhances skin suppleness, and claims are that it also acts as an anti-inflammatory agent. It is considered a non-comedogenic raw material.
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Panthenol is used as a moisturizer, soothing and softening agent.
Skin care: It improves hydration and elasticity of the
skin, reduces itching and inflammation of the skin, improves skin
elasticity, and accelerates the rate of healing of wounds. In topical
creams, it is found to be in a concentration of 1-5%.
Hair care: It binds to the hair shaft readily, so, it is a
common component of commercial shampoos and hair conditioners (in
concentrations of 0.1-1%). It coats the hair and seals its surface,
lubricating the hair shaft and giving it a shiny appearance. It can also
help protect your hair from styling or environmental damage by locking
in moisture.
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Panthenol is an alcohol derivative of pantothenic acid, a component of the B complex vitamins and an essential component of a normally functioning epithelium. Panthenol exists in two optically active forms, both of which are used in pharmaceutical preparations. While pantothenic acid is optically active, only the dextrorotatory form is biologically active. Dexpanthenol, the active form of panthenol, is enzymatically cleaved to form pantothenic acid (Vitamin B5), which is an essential component of Coenzyme A that acts as a cofactor in many enzymatic reactions that are important for protein metabolism in the epithelium.
