6(5H)-Phenanthridone
|
|
6(5H)-Phenanthridone ??
- ???
- 290-292 °C(lit.)
- ?? ?
- 435 °C
- ??
- 1.230±0.06 g/cm3(Predicted)
- ?? ??
- Sealed in dry,Room Temperature
- ???
- DMF: 1mg/mL; DMF:PBS (pH 7.2) (1:5): 0.16mg/mL
- ??? ??
- powder to crystal
- ?? ?? (pKa)
- 13.27±0.20(Predicted)
- ??
- White to Light yellow to Light orange
- ???
- DMSO(5 mg/ml)? ?????. ?? ???.
- ?? ??(λmax)
- 338nm(EtOH)(lit.)
- BRN
- 140641
- InChI
- InChI=1S/C13H9NO/c15-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)14-13/h1-8H,(H,14,15)
- InChIKey
- RZFVLEJOHSLEFR-UHFFFAOYSA-N
- SMILES
- C1=C2C(NC(=O)C3=C2C=CC=C3)=CC=C1
- CAS ??????
- 1015-89-0(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ????? | 22-24/25 | ||
|---|---|---|---|
| WGK ?? | 3 | ||
| RTECS ?? | SG0370000 | ||
| HS ?? | 29337900 | ||
| ???? ??? | 11 - Combustible Solids |
6(5H)-Phenanthridone C??? ??, ??, ??
??
6-Phenanthridone is a poly(ADP-ribose) polymerase (PARP) inhibitor with immunosuppressive effects. 6-Phenanthridone has been shown to inhibit concanavalin A-induced lymphocyte proliferation.??
ChEBI: A member of the class of phenanthridines that is phenanthridine with an oxo substituent at position 6. A poly(ADP-ribose) polymerase (PARP) inhibitor, it has been shown to exhibit immunosuppressive activity.?? ??
6-(5H)-Phenanthridinone is an inhibitor of poly(ADP-ribose)polymerase (PARP)-1 activity. The ability of 6-(5H)-phenanthridinone to potentiate the effect of ionizing radiation on tumour cells was evaluated. Action of 6-(5H)-phenanthridinone, one of the most potent PARP inhibitor, on RDM4 murine lymphoma cells in culture was evaluated.6(5H)-Phenanthridone ?? ?? ? ???
???
1,3-bis(2-phenylphenyl)urea
2-???????(2-AMINOBIPHENYL)
N-(2-????)-p-????????
2-??????-2'-??
N-methoxy-[1,1'-biphenyl]-2-carboxamide
2-???-N-???????
????
9-???????
[1,1'-???]-2-???????
carbon monoxide
???????
9-?????
???????? ??????????
??2-????????
?? ??
6(5H)-Phenanthridone ?? ??
???( 202)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Shanghai UCHEM Inc. | +86-18930848214 +86-021-56762820 |
sales@myuchem.com | China | 8886 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +86-17732866630 |
mina@chuanghaibio.com | China | 18126 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20120 | 58 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3009 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29812 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63687 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 |
sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +86-189 4982 3763 |
sales@tnjchem.com | China | 34563 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-17392587031 |
1059@dideu.com | China | 9995 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 |
gksales1@gk-bio.com | China | 9047 | 58 |
6(5H)-Phenanthridone ?? ??:
?????
2,8-DICHLORO-QUINOLINE-3-CARBALDEHYDE
2-Chloro-5-fluorobenzonitrile
N-PHENYLETHYLENEDIAMINE
Isoquinoline, 6-chloro- (6CI,9CI)
Norethindrone
Fanthridone
PJ 34 hydrochloride
6(5H)-Phenanthridone
ISOMETAMIDIUM
N-(6-OXO-5,6-DIHYDRO-PHENANTHRIDIN-2-YL)-N,N DIMETHYLACETAMIDE HYDROCHLORIDE HYDRATE
4H-CYCLOPENTA[LMN]PHENANTHRIDINE 5,9-DIONE
6(5H)-PHENANTHRIDINONE, 1,3,8,9-TETRAMETHOXY-
6(5H)-PHENANTHRIDINONE, 1,3,8,9-TETRAMETHOXY-5-METHYL-
6(5H)-PHENANTHRIDINONE, 8,9-DIMETHOXY-
2,3-DIMETHOXY-12-METHYL-12H-[1,3]DIOXOLO-[4',5':4,5]BENZO[1,2-C]PHENANTHRIDIN-13-ONE
6(5H)-PHENANTHRIDINONE, 3,8,9-TRIMETHOXY-
6(5H)-PHENANTHRIDINONE, 3,8,9-TRIMETHOXY-5-METHYL-