Carbenoxolone disodium
Carbenoxolone disodium ??
???
>275°C (dec.)
?? ??
2-8°C
???
???(?? ???), ?(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
pKa1 4.18; pKa2 5.52(at 25℃)
??
???? ?????
???
?? 100mM?? ?????.
???
???
??? ?? ??
SURFACTANT - CLEANSING SKIN CONDITIONING SURFACTANT - FOAM BOOSTING
InChIKey
BQENDLAVTKRQMS-FDPMUVMVSA-L
SMILES
[Na].[H][C@@]12C[C@](C)(CC[C@]1(C)CC[C@]3(C)C2=CC(=O)[C@]4([H])[C@@]5(C)CC[C@H](OC(=O)CCC(O)=O)C(C)(C)[C@]5([H])CC[C@@]34C)C(O)=O
LogP
7.083 (est)
CAS ??????
7421-40-1(CAS DataBase Reference)
??
?? ? ?? ??
?? ? ???? ?? (GHS)
??? ??
Xn,Xi
?? ???? ??
22-36
?????
26-36
WGK ??
3
RTECS ??
RK0250000
???? ???
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
??
LD50 in male mice (mg/kg): 198 i.v.; 120 i.p.; in male rats (mg/kg): 3200 orally (Robson, Sullivan)
????(GHS):
?? ?:
Warning
??·?? ??:
??
??·?? ??
?? ??
??
?? ?
?? ??
P- ??
H319
?? ?? ??? ???
?? ? ?? ?? ??? ??
?? 2A
??
P264, P280, P305+P351+P338,P337+P313P
??????:
P305+P351+P338
?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
Carbenoxolone disodium C??? ??, ??, ??
??? ??
White Solid
??
Anti-inflammatory glucocorticoid related to Enoxolone. Antiulcerative
?? ??
Carbenoxolone disodium is a water soluble disodium salt of glycyrrhetinic acid hemisuccinate. It acts as an efficient promoter for the nasal absorption of insulin.
???? ??
Glucocorticoid that inhibits 11 β -hydroxysteroid dehydrogenase (11-HSD) and blocks gap juntion communication.
Carbenoxolone disodium ?? ?? ? ???
???
?? ??
Carbenoxolone disodium ?? ??
???( 151)?? ??
Canada 1
China 113
Europe 2
Germany 1
India 1
Switzerland 1
United Kingdom 5
United States 26
USA 1
Global 151
Carbenoxolone disodium ?? ??: