??????
|
|
?????? ??
- ???
- >300°C (dec.)
- ?? ?
- 910.5±65.0 °C(Predicted)
- ??
- 1.656±0.06 g/cm3(Predicted)
- ?? ??
- Inert atmosphere,2-8°C
- ???
- DMSO(?? ???), ???(?? ???, ??), ???(?? ???)
- ?? ?? (pKa)
- 6.01±0.40(Predicted)
- ??? ??
- Solid
- ??
- ???
- BRN
- 380244
- ?? ??
- ????
???, ??? ?? ? ?? ??
- ??? ?? ??
- ??? ??? ??? ????
????
- InChI
- 1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H
- InChIKey
- YUSWMAULDXZHPY-UHFFFAOYSA-N
- SMILES
- C1(C2=CC=C(O)C=C2)OC2=C(C3=CC(C4OC5=CC(O)=CC(O)=C5C(=O)C=4)=CC=C3O)C(O)=CC(O)=C2C(=O)C=1
- LogP
- 3.492 (est)
- CAS ??????
- 1617-53-4(CAS DataBase Reference)
??
| ????? | 22-24/25 | ||
|---|---|---|---|
| WGK ?? | 3 | ||
| F ?????? | 10 | ||
| HS ?? | 29329990 | ||
| ???? ??? | 11 - Combustible Solids |
?????? C??? ??, ??, ??
??
Amentoflavone is a biflavonoid originally isolated from Selaginella. It has a wide variety of biological effects including antibacterial, antioxidant, antiviral, antidiabetic, and neuroprotective activities. Amentoflavone has antiviral activity against the influenza A subtypes H1N1 and H3N2, influenza B, and herpes simplex virus 1 (EC50s = 3.1 and 4.3, 0.56, and 17.9 μg/ml, respectively). It has antidiabetic effects such that it dose-dependently increases insulin receptor phosphorylation and activation and inhibits hydrolysis of p-nitrophenyl phosphate (p-NPP) catalyzed by protein tyrosine phosphatase 1B (PTP1B; IC50 = 7.3 μM). Amentoflavone reduces the time mice spend immobile in the forced swim test, a measure of antidepressant efficacy, in a dose-dependent manner.Biochem/physiol Actions
Biflavonoid with anti-inflammatory, anti-viral and cancer chemopreventive activity. It inhibits vascularization of tumors by blocking the activity of angiogenic VEGFs. Blocks the induction of COX-2 and up-regulates PPAR-γ. It is a negative modulator of the GABAA receptor at the benzodiazepine binding site.?????? ?? ?? ? ???
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?????? ?? ??
???( 342)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hangzhou ICH Biofarm Co., Ltd | +86-0571-28186870; +undefined8613073685410 |
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| BINBO BIOLOGICAL CO.,LTD | +8618629063126 |
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| career henan chemical co | +86-0371-86658258 +8613203830695 |
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| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 |
sales@biopurify.com | China | 4616 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
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| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 1287 | 58 |
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ERIODICTYOL
Naringin
Weeping Forsythia Extract CP2000
GINKGO BIFLAVONES
Rutin
BILOBETIN
Sciadopitysin
Amentoflavone 4',4''',7''-trimethyl ether
GINKGETIN
Amentoflavone 4''',7,7''-trimethyl ether
Amentoflavone 1- Amino-cyclopropane-1-acid hydrochloride
AMENTOFLAVONE-4'-METHYL ETHER
amentoflavone hexaacetate
Amentoflavone 7,4',7'',4'''-tetramethyl ether