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2-?????

2-?????
2-????? ??? ???
?? ??:
533-58-4
???:
2-?????
???(??):
2-?????
???:
2-Iodophenol
???(??):
O-IODOPHENOL;ORTHO-IODOPHENOL;DK807;NSC 9245;o-Jodfenol;2-Jodfenol;2-iodo-pheno;2-IODOPHENOL;o-iodo-pheno;2-lodophenol
CBNumber:
CB4130718
???:
C6H5IO
??? ??:
220.01
MOL ??:
533-58-4.mol

2-????? ??

???
37-40 °C (lit.)
?? ?
186-187 °C/160 mmHg (lit.)
??
1.947 g/mL at 25 °C (lit.)
???
>230 °F
?? ??
Keep in dark place,Sealed in dry,Room Temperature
???
?????(?? ???), ???????(?? ???)
??? ??
??? ?? ?? ??? ??? ???
?? ?? (pKa)
8.51(at 25℃)
??
?? ?? ????? ????
Specific Gravity
1.947
???
?? ???
??
Light Sensitive
Merck
14,5035
BRN
1855300
Henry's Law Constant
1.4×101 mol/(m3Pa) at 25℃, Abraham et al. (1994)
???
????. ?? ???? ???? ????.
InChI
1S/C6H5IO/c7-5-3-1-2-4-6(5)8/h1-4,8H
InChIKey
KQDJTBPASNJQFQ-UHFFFAOYSA-N
SMILES
Oc1ccccc1I
CAS ??????
533-58-4(CAS DataBase Reference)
NIST
Phenol, 2-iodo-(533-58-4)
EPA
Phenol, 2-iodo- (533-58-4)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn,Xi
?? ???? ?? 20/21/22-36/37/38
????? 26-36-37/39
WGK ?? 3
RTECS ?? SL5500000
TSCA TSCA listed
?? ?? IRRITANT, LIGHT SENSITIVE
HS ?? 29081000
???? ??? 11 - Combustible Solids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

2-????? MSDS


2-Iodophenol

2-????? C??? ??, ??, ??

??? ??

colorless needle-like crystals or Pale Yellow Low Melting Solid. Slightly soluble in water, easily soluble in organic solvents such as ethanol and ether.

?? ??

2-Iodophenol is a halophenol with antifungal activity. 2-Iodophenol was used in the synthesis of:
aryl 2-benzofuranyl and aryl 2-indolyl carbinols of high enantiomeric purity
3,3-disubstituted-2,3-dihydrobenzofurans
1,3,5-substituted benzenes.
2-Iodophenol is also used as additive tracers for resist plasm a etching and suzuki reaction.

?? ??

synthesis of 2-iodophenol: phenol (1a) to react with 0.5 equivalent of iodine and 1 equivalent of hydrogen peroxide in water at room temperature for 24 h, 2,6-diiodophenol (2a) and 2-iodophenol (3) were isolated in yields of 21 and 49%, respectively.
synthesis of 2-iodophenol

?? ??

Rapid palladium-catalyzed carbonylative cyclization reactions of 2-iodophenol with various alkyne under microwave irradiation using Mo(CO)6 as the CO source has been investigated.

Purification Methods

Crystallise 2-iodophenol from CHCl3 or diethyl ether. The acetate has m 65-66o (from MeOH). [Beilstein 6 H 208, 6 II 198, 6 III 774, 6 IV 1074.]

2-????? ?? ?? ? ???

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2-????? ?? ??

???( 452)?? ??
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2-????? ?? ??:

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