ChemicalBook >?? ???? >5-??????
5-??????
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5-?????? ??
- ??
- 1.65±0.1 g/cm3(Predicted)
- ?? ??
- Sealed in dry,Store in freezer, under -20°C
- ??? ??
- Solid
- ?? ?? (pKa)
- 8+-.0.10(Predicted)
- ??
- White to off-white
- ?? ??(λmax)
- 279 (pH 2)；277 (pH 12)
- InChI
- InChI=1S/C10H14N2O7/c1-18-4-2-12(10(17)11-8(4)16)9-7(15)6(14)5(3-13)19-9/h2,5-7,9,13-15H,3H2,1H3,(H,11,16,17)/t5-,6-,7-,9-/m1/s1
- InChIKey
- ZXIATBNUWJBBGT-JXOAFFINSA-N
- SMILES
- OC[C@H]1O[C@@H](N2C=C(OC)C(=O)NC2=O)[C@H](O)[C@@H]1O
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| WGK ?? | 3 | ||
|---|---|---|---|
| HS ?? | 29349990 |
| ????(GHS): |
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5-?????? C??? ??, ??, ??
??? ??
Solid??
5-Methoxyuridine is an analog of Uridine (U829910) and is used as a reagent in the synthesis of 5-OMe-UDP, a potent and selective P2Y6-receptor agonist.??
ChEBI: A derivative of uridine, bearing an additional methoxy substituent at position 5 on the uracil ring.Synthesis
5-Hydroxyuridine was synthesized by the method described by T. Ueda. 5-Hydroxyuridine (30 mg) was further methylated by 20 y1 of dimethyl sulfate in 0.6 ml of 0.1 N NaOH. A reaction mixture was chromatographed on Whatman 3MM paper using solvent D. The band containing 5-Hydroxyuridine was extracted with water and the extract was further purified by paper chromatography in sol vent E. These procedures gave a 25% yield of mo5l). In addition to 5-Hydroxyuridine and the raw material, the methylated products contained 5% of 5-hydroxy-3-methyl uridine and 4% of 5-methoxy-3-methyluridine.5-?????? ?? ?? ? ???
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5-?????? ?? ??
???( 95)?? ??
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5-?????? ?? ??:
?????? (2-??????)?? ????? ??? ??????-1-???? ??????-1,2-????? ?????? ???
N-Butylurea
3-Methylamino-1,2-propanediol
4,6-Dihydroxy-5-methoxypyrimidine
(E)-3-(Dimethylamino)-2-methoxyacrylaldehyde
2',3'-Dideoxyuridine
5-HYDROXYURIDINE
N-(2-METHOXYETHYL)UREA
5-METHOXYURIDINE
1-METHYLURACIL
3'-DEOXYURIDINE
N-hydroxymethyl-N-methylformamide