5-??????[C][1,2]????-1(3H)-OL
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![5-??????[C][1,2]????-1(3H)-OL](CAS/GIF/174671-46-6.gif)
5-??????[C][1,2]????-1(3H)-OL ??
- ???
- 120-122℃
- ?? ?
- 230.8±50.0 °C(Predicted)
- ??
- 1.28±0.1 g/cm3(Predicted)
- ?? ??
- -20°C
- ???
- DMSO(?? ???), ???(?? ???)
- ?? ?? (pKa)
- 6.81±0.20(Predicted)
- ??? ??
- ??
- ??
- ???? ????
- ???
- ???
- InChI
- InChI=1S/C7H6BFO2/c9-6-1-2-7-5(3-6)4-11-8(7)10/h1-3,10H,4H2
- InChIKey
- LFQDNHWZDQTITF-UHFFFAOYSA-N
- SMILES
- B1(O)C2=CC=C(F)C=C2CO1
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| WGK ?? | WGK 3 | ||
|---|---|---|---|
| HS ?? | 2934999090 | ||
| ???? ??? | 11 - Combustible Solids | ||
| ?? ?? ??? | 174671-46-6(Hazardous Substances Data) |
5-??????[C][1,2]????-1(3H)-OL C??? ??, ??, ??
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Tavaborole (Kerydin®), discovered and developed by Anacor, was approved by the US FDA in July 2014. Tavaborole, topical solution, 5% is an oxaborole antifungal indicated for the treatment of onychomycosis of the toenails due to Trichophyton rubrum or Trichophyton mentagrophytes. The mechanism of action of tavaborole is inhibition of fungal protein synthesis, which inhibits an aminoacyl-transfer ribonucleic acid synthetase.??
Tavaborole is a topical treatment of toenail onychomycosis.??
ChEBI: A member of the class of benzoxaboroles that is 1,3-dihydro-1-hydroxy-2,1-benzoxaborole substituted at position 5 by a fluoro group. A topical antifungal agent used for the treatment of onychomycosis (fungal infection of the toenails and fingernails).?? ??
Tavaborole is a boron-based pharmaceutical agent. It has broad-spectrum oxaborole antifungal activity. Due to its low molecular weight, it facilitates maximal nail plate penetration than its predecessors.5-??????[C][1,2]????-1(3H)-OL ?? ?? ? ???
???
5-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzaldehyde
Benzene, 1-bromo-2-[(1-ethoxyethoxy)methyl]-4-fluoro-
Reaxys ID: 10668384
4-Fluoro-2-methylphenylboronic acid
(4-????-2-(??????)??)???
2-???-5-????-[1-(??????)??]??
??????????????
?
??
2-Bromo-5-fluorobenzyl alcohol
?? ??
5-??????[C][1,2]????-1(3H)-OL ?? ??
???( 240)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hefei Lbao Physical & Chemical Science Co.,Ltd | +15184799099 |
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contact@fuxinpharm.com | China | 10000 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
marketing@targetmol.com | United States | 32466 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 |
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| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6312 | 58 |
| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 |
sales@myuchem.com | China | 8740 | 58 |
5-??????[C][1,2]????-1(3H)-OL ?? ??:
6-aMinobenzo[c][1,2]oxaborol-1(3H)-ol
Vaniprevir
2-(Hydroxymethyl)-6-methoxyphenylboronic acid dehydrate
(2-HYDROXYMETHYL-5-NITRO)BENZENEBORONIC ACID DEHYDRATE
2,1-Benzoxaborole,1,3-dihydro-1-hydroxy-6-Methoxy
benzo[c][1,2]oxaborole-1,6(3H)-diol
6-chlorobenzo[c][1,2]oxaborol-1(3H)-ol
7-fluorobenzo[c][1,2]oxaborol-1(3H)-ol
5-(TRIFLUOROMETHYL)BENZO[C][1,2]OXABOROL-1(3H)-OL
6-FLUOROBENZO[C][1,2]OXABOROL-1(3H)-OL
4-aminobenzo[c][1,2]oxaborol-1(3H)-ol
5-aminobenzo[c][1,2]oxaborol-1(3H)-ol
ISOINDOLIN-4-OL HYDROCHLORIDE
7-aminobenzo[c][1,2]oxaborol-1-(3H)-ol
1-Hydroxy-2,1-benzoxaborolane
4-Fluoro-2-methylphenylboronic acid
Tavaborole