ChemicalBook >?? ???? >???>??? ??>???>N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE
N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE
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N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE ??
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- Store at -20°C
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- DMF: 30 mg/mL; DMSO: 30 mg/mL; Ethanol: 3 mg/mL
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- White to light yellow
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N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE C??? ??, ??, ??
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W-54011 is an orally bioavailable, nonpeptide antagonist of complement component 5a receptor 1 (C5aR), also known as cluster of differentiation 88 (CD88). W-54011 inhibits 125I-rhC5a binding in neutrophils (Ki = 2.2 nM) and C5a-mediated intracellular Ca2+ mobilization (IC50 = 3.1 nM). W-54011 is selective and does not affect Ca2+ mobilization mediated by other G protein-coupled receptor (GPCR) ligands, N-Formyl-Met-Leu-Phe (fMLF; ), or IL-8 up to a concentration of 10 μM. It inhibits Ca2+ mobilization in neutrophils in humans, cynomolgus monkeys, and gerbils, but not in mice, rats, guinea pigs, rabbits, or dogs. At 10 nM, W-54011 also inhibits C5a-mediated migration and vessel formation of human microvascular endothelial cells (HMEC-1).??
W 54011 is a potent orally active non-peptide C5a receptor antagonist.N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE ?? ?? ? ???
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N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE ?? ??
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| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
marketing@targetmol.com | United States | 32466 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 |
masar@topule.com | China | 8467 | 58 |
| Aladdin Scientific | |
tp@aladdinsci.com | United States | 57505 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 |
info@chemexpress.com | China | 7552 | 61 |
| Bide Pharmatech Ltd. | 400-400-164-7117 18317119277 |
product02@bidepharm.com | China | 40000 | 60 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 |
info@efebio.com | China | 9804 | 58 |
| Guangzhou QiYun Biotechnology Co., Ltd. | 020-61288194 61288195 |
505721671@qq.com | China | 3866 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 |
3008007409@qq.com | China | 89686 | 60 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 |
3193328036@qq.com | China | 29660 | 68 |
| Nanjing KaiMubo Pharmaceutical Co., Ltd. | 025-66162170 |
China | 7181 | 55 |
N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE ?? ??:
BenzenesulfonaMide, 4-chloro-N-[1-(2-phenylethyl)-2-piperidinylidene]-
(S)-3-aMino-4-(3-hexylphenylaMino)-4-oxobutylphosphonic acid (TFA salt)
W-5 HYDROCHLORIDE
W123 Exclusive
N-(4-AMINOBUTYL)-5-CHLORO-2-NAPHTHALENESULFONAMIDE HYDROCHLORIDE
[(3R)-3-Amino-4-[(3-hexylphenyl)amino]-4-oxobutyl]-phosphonic acid mono(trifluoroacetate)
P-ISOPROPYL-PHENYL-P-TOLYL-AMINE
C-(1,2,3,4-TETRAHYDRO-NAPHTHALEN-1-YL)-METHYLAMINE HYDROCHLORIDE
N-[[4-(DIMETHYLAMINO)PHENYL]METHYL]-1,2,3,4-TETRAHYDRO-7-METHOXY-N-[4-(1-METHYLETHYL)PHENYL]-1-NAPHTHALENECARBOXAMIDE HYDROCHLORIDE
[(4-(DIMETHYLAMINO)PHENYL)METHYL](4-ISOPROPYLPHENYL)AMINE