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???????????????? ??? ???
?? ??:
79416-27-6
???:
????????????????
???(??):
????????????????;5-?????????????????????
???:
5-Aminolevulinic acid methyl ester hydrochloride
???(??):
METHYL 5-AMINOLEVULINATE HYDROCHLORIDE;Methyl 5-amino-4-oxopentanoate hydrochloride;5-ALA MEL;H-TIC(OTBU)-OH APTS;Methyl Aminolevulinate HCl;Methyl 5-Aminolevulinate HCl;ALA METHYL ESTER HYDROCHLORIDE;Aminolevulinic Acid Impurity 1;5-ALA methyl ester hydrochloride;5-Aminolevulinic acid methyl este
CBNumber:
CB4373830
???:
C6H12ClNO3
??? ??:
181.62
MOL ??:
79416-27-6.mol
MSDS ??:
SDS

???????????????? ??

???
119-121°
?? ??
2-8°C
???
DMSO(?? ???), ???(?? ???), ?(?? ???)
??? ??
??
??? ??
??? ??
??
???? ?????
???
?? ?? ?? ??
??
Light Sensitive/Hygroscopic
???
???
??? ?? ??
?? ??
????
??
InChI
InChI=1S/C6H11NO3.ClH/c1-10-6(9)3-2-5(8)4-7;/h2-4,7H2,1H3;1H
InChIKey
UJYSYPVQHFNBML-UHFFFAOYSA-N
SMILES
C(=O)(CN)CCC(=O)OC.Cl
CAS ??????
79416-27-6(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 26-36
WGK ?? 3
HS ?? 29225090
???? ??? 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
0
2 0

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5-Aminolevulinic acid methyl ester hydrochloride is white powder

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5-Aminolevulinic acid methyl ester hydrochloride is used in photodynamic therapy.

??

ChEBI: The hydrochloride salt of methyl 5-aminolevulinate. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells.

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