Levosulpiride
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Levosulpiride ??
- ???
- 183-186 °C(lit.)
- ??
- 1.236±0.06 g/cm3(Predicted)
- ?? ??
- 2-8°C
- ???
- DMF(?? ???), DMSO(?? ???), ???(?? ???)
- ?? ?? (pKa)
- 9.98±0.60(Predicted)
- ??? ??
- Solid
- ??
- ???? ?????
- Merck
- 14,8989
- ?? ??
- ??? ? ???
???(???)
- InChI
- 1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
- InChIKey
- BGRJTUBHPOOWDU-NSHDSACASA-N
- SMILES
- CCN1CCC[C@H]1CNC(=O)c2cc(ccc2OC)S(N)(=O)=O
- CAS ??????
- 23672-07-3(CAS DataBase Reference)
Levosulpiride C??? ??, ??, ??
??? ??
White Solid??
Dopamine D2 and D3-receptor antagonist. Antipsychotic; antidepressant; antiemetic.??
ChEBI: An optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 muM at D2, D3, D4, 1 and D5 receptors respectively).?? ??
(S)-()-Sulpiride is a levorotatory enantiomer of sulpiride, which shows greater central antidopaminergic activity, antiemetic and antidyspeptic effects. It is also used as a therapeutic drug for the treatment of depression and somatoform disorders.???? ??
Active enantiomer. Selective D 2 -like dopamine antagonist (K i values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 μ M at D 2 , D 3 , D 4 , D 1 and D 5 receptors respectively).Levosulpiride ?? ?? ? ???
???
Lithium tert-butoxide
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Aminosulfonate
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(S)-2-(?????)-1-??????
2-(Aminomethyl)-1-ethylpyrrolidine
L-(-)-???
??? ?????
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Levosulpiride ?? ??
???( 435)?? ??
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