5-Bromo-2-chloropyrimidine
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5-Bromo-2-chloropyrimidine ??
- ???
- 73-79 °C (lit.)
- ?? ?
- 95°C 15mm
- ??
- 1.859±0.06 g/cm3(Predicted)
- ???
- 95°C/15mm
- ?? ??
- Keep in dark place,Sealed in dry,Room Temperature
- ???
- ???? ???
- ?? ?? (pKa)
- -2.84±0.22(Predicted)
- ??? ??
- ??? ??
- ??
- ???? ?????
- ???
- ???
- BRN
- 507955
- ???
- ???
- InChI
- InChI=1S/C4H2BrClN2/c5-3-1-7-4(6)8-2-3/h1-2H
- InChIKey
- XPGIBDJXEVAVTO-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=C(Br)C=N1
- CAS ??????
- 32779-36-5(CAS DataBase Reference)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38 | ||
| ????? | 26-36/39-37/39-36 | ||
| ????(UN No.) | UN 3335 | ||
| WGK ?? | 3 | ||
| ?? ?? | IRRITANT | ||
| HS ?? | 29335990 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Eye Irrit. 2 Skin Irrit. 2 STOT SE 3 |
5-Bromo-2-chloropyrimidine C??? ??, ??, ??
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5-Bromo-2-chloropyrimidine is a halogenated pyrimidine analogue containing chloro and bromo substituents at positions 2 and 5 of the benzene ring structure. The compound is used as a pharmaceutical intermediate in the preparation of macitentan, an endothelin receptor antagonist drug for the treatment of pulmonary hypertension.??? ??
Off-white to beige crystalline powder??
5-Bromo-2-chloropyrimidine is a intermediate in the synthesis of pharmaceutical goods such as inhibitors.5-Bromo-2-chloropyrimidine ?? ?? ? ???
???
5-Bromo-2-hydroxypyrimidine
5-Bromopyrimidine
2-Chloropyrimidine
trichlorophosphate
4-Bromo-N,N-dimethylaniline
N,N'-??????????
?? ??
5-BROMO-2-ETHOXY-PYRIMIDINE
5-Bromopyrimidine-2-carbonitrile
5-BROMO-2-(DIMETHYLAMINO)PYRIMIDINE
5-BROMOPYRIMIDINE-2-CARBOXYLIC ACID
(5-???-????-2-?)-???-??
5-BROMO-2-(METHYLAMINO)PYRIMIDINE
2-CHLOROPYRIMIDINE-5-BORONIC ACID
5-BROMO-2-(PYRROLIDIN-1-YL)PYRIMIDINE
2-CHLORO-5-PHENYL-PYRIMIDINE
2-???????-5-??????
5-Bromo-2-methoxypyrimidine
tert-????2-(5-???????-2-?)?????
N-(5-BroMopyriMidin-2-yl)-N-MethylacetaMide
5-Bromo-2-chloropyrimidine ?? ??
???( 765)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
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5-Bromo-2-chloropyrimidine ?? ??:
3-?????? ???? ???? ????????? ??
2-Chloropyrimidine
5-Bromopyrimidine
5-Bromo-2-iodopyrimidine
Chlorobromoisocyanurate
4-BENZYLOXY-5-BROMO-2-CHLOROPYRIMIDINE
4-AMINO-5-BROMO-2-CHLOROPYRIMIDINE, 95+%,4-AMINO-5-BROMO-2-CHLOROPYRIMIDINE
5-Bromo-2,4-dichloropyrimidine
5-bromo-2-chloro-4-morpholinopyrimidine
5-Bromo-2-chloro-4-(dimethylamino)pyrimidine
5-Bromo-2,4-dichloro-6-methylpyrimidine
5-BROMO-2-CHLORO-4-METHOXYPYRIMIDINE
5-BROMO-2-CHLORO-4-(1-PIPERIDINYL)PYRIMIDINE
2-Bromo-5-chloropyrimidine
2-Chloro-4-bromopyridine