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Loxoprofen sodium

Loxoprofen sodium ??? ???
?? ??:
80382-23-6
???:
Loxoprofen sodium
???(??):
Loxoprofen sodiuM hydrate;Loxonin;LOXOPROFEN NA;LXP;cs-600;loxoprofern sodium;Loxoprofen Sodium impurity;Sodium 2-(4-((2-oxocyclopentyl)methyl)phenyl)propanoate;Unastin;Dipyridame
CBNumber:
CB5138100
???:
C15H19NaO3
??? ??:
270.3
MOL ??:
80382-23-6.mol

Loxoprofen sodium ??

?? ??
Inert atmosphere,Room Temperature
???
DMSO: ??? ? ??
??? ??
??
??
White to off-white
InChI
InChI=1S/C15H18O3.Na.H/c1-10(15(17)18)12-7-5-11(6-8-12)9-13-3-2-4-14(13)16;;/h5-8,10,13H,2-4,9H2,1H3,(H,17,18);;
InChIKey
ALZXNWUYLUBHJL-UHFFFAOYSA-N
SMILES
C(C1CCCC1=O)C1C=CC(C(C)C(=O)O)=CC=1.[NaH]
CAS ??????
80382-23-6(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

Loxoprofen sodium C??? ??, ??, ??

??

Loxoprofen sodium i s an antiinflammatory/analgesic agent useful in the management of rheumatoid arthritis and related disorders. It is converted in vivo to the corresponding trans-hydroxycyclopentane analog, through which it appears to exert its activity.

??

anti-inflammatory

??

ChEBI: A hydrate that is the dihydrate form of loxoprofen sodium. The parent acid, loxoprofen, is a prodrug that is rapidly converted to its active trans-alcohol metabolite following oral administration.

???

Adverse effects include anorexia, nausea, vomiting, bleeding, anemia, diarrhea, and constipation.

Loxoprofen sodium ?? ?? ? ???

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Loxoprofen sodium ?? ??

???( 480)?? ??
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Loxoprofen sodium ?? ??:

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