Bis(trimethylsilyl)trifluoroacetamide
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Bis(trimethylsilyl)trifluoroacetamide ??
- ???
- -10°C
- ?? ?
- 45-50 °C14 mm Hg(lit.)
- ??
- 0.97 g/mL(lit.)
- ???
- n
20/D 1.384(lit.)
- ???
- 75 °C
- ?? ??
- 2-8°C
- ???
- ?????? ?? ??.
- ??? ??
- ??
- ?? ?? (pKa)
- 1.82±0.50(Predicted)
- Specific Gravity
- 0.971
- ??
- ??~???
- ???
- ????
- Hydrolytic Sensitivity
- 8: reacts rapidly with moisture, water, protic solvents
- ??
- Moisture Sensitive
- BRN
- 3607620
- ???
- ??? ???
- InChI
- 1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3/b12-7+
- InChIKey
- XCOBLONWWXQEBS-KPKJPENVSA-N
- SMILES
- C[Si](C)(C)O\C(=N\[Si](C)(C)C)C(F)(F)F
- CAS ??????
- 25561-30-2(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | C,F,T | ||
|---|---|---|---|
| ?? ???? ?? | 11-34-10-35-14 | ||
| ????? | 26-36/37/39-45-16 | ||
| ????(UN No.) | UN 2924 3/PG 3 | ||
| WGK ?? | 3 | ||
| F ?????? | 10-21 | ||
| ?? ?? ?? | Flammable/Moisture Sensitive | ||
| TSCA | Yes | ||
| ?? ?? | 3 | ||
| ???? | III | ||
| HS ?? | 29310095 | ||
| ???? ??? | 3 - Flammable liquids | ||
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Flam. Liq. 2 Skin Corr. 1A |
Bis(trimethylsilyl)trifluoroacetamide C??? ??, ??, ??
??? ??
Clear to yellowish clear liquid??
N,O-Bis(trimethylsilyl)trifluoroacetamide is used for analytical purposes or as a chemical reagent for synthesis of more complex molecules. It is silylation reagent useful in GC and GC-MS for the derivatization of a wide range of functional groups under mild conditions. It is also used as DAT inhibitor and a SLC6A2 inhibitor. It is routinely used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids and amides.??
ChEBI: A silyl ether that is the N,O-bis(trimethylsilyl) derivative of trifluoroacetamide. N,O-bis(trimethylsilyl)trifluoroacetamide is a derivatisation agent used in gas chromatography/m ss spectrometry applications.?? ??
Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane has found application to be used in gas chromatography (GC) and mass-spectrometry (MS). It can also be used in HPLC- electrochemical detection assay of 8-oxo-deoxyguanosine and8-oxo-guanine.Bis(trimethylsilyl)trifluoroacetamide ?? ?? ? ???
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Bis(trimethylsilyl)trifluoroacetamide ?? ??
???( 597)?? ??
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