Pyridazine
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Pyridazine ??
- ???
- -8 °C (lit.)
- ?? ?
- 208 °C (lit.)
- ??
- 1.103 g/mL at 25 °C (lit.)
- ???
- n
20/D 1.524(lit.)
- ???
- 185 °F
- ?? ??
- Inert atmosphere,Room Temperature
- ??? ??
- ??
- ?? ?? (pKa)
- 2.24(at 20℃)
- ??
- ?? ???
- ???
- ?? ??
- Merck
- 14,7969
- BRN
- 103906
- InChI
- 1S/C4H4N2/c1-2-4-6-5-3-1/h1-4H
- InChIKey
- PBMFSQRYOILNGV-UHFFFAOYSA-N
- SMILES
- c1ccnnc1
- CAS ??????
- 289-80-5(CAS DataBase Reference)
- NIST
- Pyridazine(289-80-5)
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38-22 | ||
| ????? | 23-24/25 | ||
| ????(UN No.) | NA 1993 / PGIII | ||
| WGK ?? | 3 | ||
| RTECS ?? | UR5267000 | ||
| F ?????? | 8-10 | ||
| TSCA | TSCA listed | ||
| HS ?? | 29339980 | ||
| ???? ??? | 10 - Combustible liquids | ||
| ?? | LD50 ipr-mus: 2650 mg/kg PBPHAW 1,542,65 |
Pyridazine C??? ??, ??, ??
??? ??
Pyridazine is a nitrogen-containing six-membered heterocyclic compound belonging to the azine class, being an isomer of pyrimidine and pyrazine. It exists as a clear yellowish-brown liquid, insoluble in petroleum ether but readily soluble in methanol, ethanol, and diethyl ether. It is miscible with water, benzene, and dimethylformamide. Pyridazine is a weak base capable of forming salts with picric acid, hydrochloric acid, and similar compounds. It exhibits limited reactivity towards aromatic nucleophilic and electrophilic substitution reactions and demonstrates stability towards potassium permanganate. Reduction with sodium or alcohols cleaves the chain, converting it into 1,4-diaminobutane.??
Pyrrolo[1,2-b]pyridazine 1 is a N-bridgehead aromatic heterocycle containing two nitrogen atoms, is obtained by the condensation of pyridazine and pyrrole.?? ??
Pyridazine is obtained by the condensation of butenedial and hydrazine. ??? ??
Pyridazine is a mono-basic 1,2-diazine compound, which is commonly prepared by the reaction of 1,4-dicarbonyls with hydrazines. Pyridazine ring is found in many herbicides like credazine, pyridatol and many pharmaceutical drugs like cefozopran, olaparib, talazoparib, and cadralazine.Safety Profile
Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic vapors of NOx.Pyridazine ?? ?? ? ???
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Cyclobutene, 3,4-dichloro-, (3R,4R)-rel-
P-XYLENE-D10
3-CHLOROPYRIDAZINE
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Pyridazine ?? ??
???( 263)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20122 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29640 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21586 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29812 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | +8618957127338 |
stella@zetchem.com | China | 2994 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 |
joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Xi'an Yutbon Pharmaceutical Technology Co., Ltd | 029-81140587 +8618717328141 |
sales@yutbon.com | China | 454 | 58 |
| Shanghai Rlavie Technology Co ltd | +86-021-67759270 +8617717059219 |
sales@rlavie.com | China | 1030 | 58 |
Pyridazine ?? ??:
3,6-???????? 3-(4-??????????)-6-??????? ???? ??? ???????
3-Chloro-6-methylpyridazine
ETHYL 4-PYRIDAZINECARBOXYLATE
pyridazine-4-boronic acid pinacol ester
3-Pyridazinecarboxylic acid
pyridazine-3-carbonitrile
PYRIDAZINE-4-CARBALDEHYDE
Pyridazine-4-carboxylic acid methyl ester
2-(TERT-BUTYL)-4,5-DICHLORO-2,3-DIHYDROPYRIDAZIN-3-ONE
Pyridazin-3-ylmethanol
1,4-Dichlorophthalazine
3,6-Dichloro-4-methylpyridazine
BENZO[C]CINNOLINE
SULFACHLOROPYRIDAZINE
1-CHLOROPHTHALAZINE