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????? ??????

????? ??????
????? ?????? ??? ???
?? ??:
1445-45-0
???:
????? ??????
???(??):
???????????;????? ??????
???:
Trimethyl orthoacetate
???(??):
TMOA;1,1,1-TRIMETHOXYETHANE;CH3C(OCH3)3;orthoacetate;Ethane, 1,1,1-trimethoxy-;Methyl orthoacetate;Trimethylorthoaceate;Trimethylorthoacetat;trimethyl-acetate;Trimethyl o-acetate
CBNumber:
CB5759743
???:
C5H12O3
??? ??:
120.15
MOL ??:
1445-45-0.mol
MSDS ??:
SDS

????? ?????? ??

?? ?
107-109 °C(lit.)
??
0.944 g/mL at 25 °C(lit.)
???
20 hPa (20 °C)
???
n20/D 1.388(lit.)
???
62 °F
?? ??
Store below +30°C.
???
?????(???? ??), ???(?? ???)
??? ??
??
??
??? ??~?? ??
Specific Gravity
0.960 (20/4℃)
???
?? ??
??
Moisture Sensitive
BRN
1098338
Henry's Law Constant
6.4×10-1 mol/(m3Pa) at 25℃, Guthrie (1973)
InChI
1S/C5H12O3/c1-5(6-2,7-3)8-4/h1-4H3
InChIKey
HDPNBNXLBDFELL-UHFFFAOYSA-N
SMILES
COC(C)(OC)OC
LogP
1.13 at 25℃
CAS ??????
1445-45-0(CAS DataBase Reference)
NIST
Ethane, 1,1,1-trimethoxy-(1445-45-0)
EPA
Trimethyl orthoacetate (1445-45-0)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? F,Xi
?? ???? ?? 11-43-38-36/37/38
????? 16-37/39-24-33-26-7/9
????(UN No.) UN 3272 3/PG 2
WGK ?? 1
TSCA TSCA listed
?? ?? 3
???? II
HS ?? 29159080
???? ??? 3 - Flammable liquids
Hazard Classifications Eye Irrit. 2
Flam. Liq. 2
Skin Sens. 1B
?? LD50 orally in Rabbit: > 2000 mg/kg
???? ?? KE-34616
????(GHS): Flame (GHS02)Exclamation Mark (GHS07)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H225 ???? ?? ? ?? ??? ?? ?? 2 ?? P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
??????:
P210 ?·???·??·????? ????? - ?? ???.
P233 ??? ??? ?????. ??? ??? ? ?? ?? ??? ???? ?????.
P240 ??? ????? ?? ? ??????.
P241 ?? ??? ??[???/??/??/...]?(?) ?????.
P242 ???? ???? ?? ??? ?????
P243 ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
P370+P378 ?? ? ?? ?? ?? (Section 5. ??, ??? ????? ??? ???)?(?) ?????.
P403+P235 ??? ? ?? ?? ???? ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
3
2 1

????? ?????? MSDS


Trimethyl orthoacetate

????? ?????? C??? ??, ??, ??

??? ??

CLEAR COLOURLESS TO SLIGHTLY BROWN LIQUID

??

Trimethyl orthoacetate has been used in the preparation of 2-amino-9-(3-acyloxymethyl-4-alkoxycarbonyloxybut-1-yl)purines and 2-amino-9-(3-alkoxycarbonyl-oxymethyl-4-alkoxycarbonyloxybut -1-yl)purines.

?? ??

Kinetics and mechanism of gas-phase elimination of trimethyl orthoacetate has been examined over the temperature range of 310-369°C and pressure range of 50-130Torr.

????? ?????? ?? ?? ? ???

???

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