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5-??????????

5-??????????
5-?????????? ??? ???
?? ??:
2493-04-1
???:
5-??????????
???(??):
5-??????????
???:
5-NITROFURFURYL ALCOHOL
???(??):
5-Nitrofuryl alcohol;(5-Nitrofuran-2-yl);5-nitro-furfurylalcoho;5-nitro-2-furanmethano;5-NITROFURFURYL ALCOHOL;5-nitro-2-furanmethanol;2-Furanmethanol, 5-nitro-;5-NITRO-2-FURFURYL ALCOHOL;(5-nitrofuran-2-yl)methanol;2-Furanmethanol, 5-nitro- (9CI)
CBNumber:
CB6200787
???:
C5H5NO4
??? ??:
143.1
MOL ??:
2493-04-1.mol

5-?????????? ??

???
30-32 °C
?? ?
104-105 °C/3 mmHg (lit.)
??
1.283 g/mL at 25 °C (lit.)
???
n20/D 1.582(lit.)
???
>230 °F
?? ??
2-8°C
?? ?? (pKa)
13.46±0.10(Predicted)
??? ??
??
??? ??
??? ??
??
??
InChI
1S/C5H5NO4/c7-3-4-1-2-5(10-4)6(8)9/h1-2,7H,3H2
InChIKey
NDSTUUPEXNCUNW-UHFFFAOYSA-N
SMILES
OCc1ccc(o1)[N+]([O-])=O
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 20/21/22-36/37/38
????? 26-36
WGK ?? 3
RTECS ?? LU9174000
HS ?? 2932190090
???? ??? 10 - Combustible liquids
Hazard Classifications Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H312 ??? ???? ??? ?? ?? ?? - ?? ?? 4 ?? P280,P302+P352, P312, P322, P363,P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H332 ???? ??? ?? ?? ?? ?? ?? 4 ?? P261, P271, P304+P340, P312
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P280 ????/???/???/?????? ?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

5-?????????? C??? ??, ??, ??

??

Nitrofurfuryl alcohol has been used as an antibacterial, antiprotozoal, and antihelminthic drug in human and animals. The mechanism of nitrofurfuryl alcohol toxicity is not clear but the nitro group is believed responsible for the carcinogenicity and mutagenicity of nitrofurfuryl alcohol.

??

5-Nitrofurfuryl alcohol was used to investigate the reduction of some 2-substituted-5-nitrofuran compounds by rhodium complex [Rh(COD)(2-picoline)2](PF6) (COD = 1,5-cyclooctadiene) anchored on poly(4-vinylpyridine). It may be used for the synthesis of 5-nitrofurfuryl bromide and 5-nitrofurfurylamine hydrochloride.

????

Hazardous decomposition products formed under fire conditions are carbon oxides and nitrogen oxides.

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