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?? ??:: 446-48-0

???:: ??????????

???(??):: ??????????;2-?????? ?????

???:: 2-Fluorobenzyl bromide

???(??):: 1-(BROMOMETHYL)-2-FLUORO-BENZENE;2-Fluorobenzyl bromi;O-FLUOROBENZYL BROMIDE;2-FLUOROBENZYL BROMIDE;2-Fluarobenzyl bromide;à-bromo-2-fluorotoluene;2-FluorobenzylBromide>α-Bromo-2-fluorotoluene;2- fluorinebenzyl broMide;2-Fluorobenzylbromide,98%

CBNumber:: CB6348784

???:: C7H6BrF

??? ??:: 189.02

MOL ??:: 446-48-0.mol

MSDS ??:: SDS

MSDS

?? ?? 421

?????????? ??

?? ?: 84-85 °C15 mm Hg(lit.)

??: 1.567 g/mL at 25 °C(lit.)

???: n20/D 1.552(lit.)

???: 181 °F

?? ??: under inert gas (nitrogen or Argon) at 2-8°C

???: ?????(?? ???), ???(?? ???)

??? ??: ??

Specific Gravity: 1.567

??: ????~???

??: Lachrymatory

BRN: 1099894

InChI: InChI=1S/C7H6BrF/c8-5-6-3-1-2-4-7(6)9/h1-4H,5H2

InChIKey: FFWQLZFIMNTUCZ-UHFFFAOYSA-N

SMILES: C1(CBr)=CC=CC=C1F

CAS ??????: 446-48-0(CAS DataBase Reference)

NIST: 2-Fluorobenzyl bromide(446-48-0)

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	C
?? ???? ??	34-36/37
?????	23-26-27-36/37/39-45
????(UN No.)	UN 3265 8/PG 2
WGK ??	3
?? ?? ??	Corrosive/Lachrymatory
?? ??	8
????	III
HS ??	29039990
???? ???	8A - Combustible corrosive hazardous materials
Hazard Classifications	Skin Corr. 1B STOT SE 3

????(GHS):

?? ?:

Danger

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H314	??? ?? ??? ?? ??? ???	????? ?? ?????	?? 1A, B, C	??		P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P271	?? ?? ??? ? ?? ???? ?????.
P280	????/???/???/?????? ?????.
P303+P361+P353	??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

NFPA 704

	2
3		0

?????????? MSDS

2-Fluorobenzyl bromide

?????????? C??? ??, ??, ??

??? ??

clear colorless to slightly yellow liquid

??

2-Fluorobenzyl bromide was used:

in the synthesis of 2-pyrrolo[2,3-d]pyrimidines
as alkylating agent during the synthesis of 8-alkylated imidazolo[1,2-a]pyrimid-5-ones
in the synthesis of prasugrel

?????????? ?? ?? ? ???

???

?? ??

(2-FLUORO-PHENYL)-METHANESULFONYL CHLORIDE ETHYL 2-FLUOROPHENYLACETATE 2-?????-1-????-4-????? ???????2-???????? 2-FLUORO-DL-PHENYLALANINE (2-FLUORO-BENZYL)-HYDRAZINE 1-(2-fluorobenzyl)piperidin-4-ol N-??-2-????-N-??????? Benzenemethanamine, 2-fluoro-N-[(4-fluorophenyl)methyl]-N-methyl- 2-?????????? 1-[(2-??????)??]-1H-??-2,3-?? Benzene, 2-chloro-1-[(2-fluorophenyl)methoxy]-4-nitro- 2-????????????????

?????????? ?? ??

???( 421)?? ??

???	??	???	??	?? ?	??
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?????????? ?? ??:

?????????? ??? ????? ????? ????????? ??????? ??????? 2,2-???-3-(1-???-1-?)??????????? [2,3,5,6-???????-4-(?????)??]?? ?????????? ??????????????? ?? ???????????? ?????????? ??? ?? ??????(2-) ??-???-2,6-???????? ?????????? 2-????-4-?????????? 2-???-1-(?????)-4-??????

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