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????(200MG)

????(200MG)
????(200MG) ??? ???
?? ??:
1403-17-4
???:
????(200MG)
???(??):
????(200MG)
???:
Candicidin
???(??):
Candicidin complex;candimon;NSC94219;CARBOPRST;candeptin;Levorinum;NSC 94219;NSC-94219;candizidin;candicidin
CBNumber:
CB6501392
???:
C21H36O5
??? ??:
368.51
MOL ??:
1403-17-4.mol
MSDS ??:
SDS

????(200MG) ??

?? ?
878.79°C (rough estimate)
??
1.1100 (rough estimate)
???
1.6200 (estimate)
?? ??
Store at -20°C
???
DMSO:4.9(Max Conc. mg/mL);10.08(Max Conc. mM)
Ethanol:12.5(Max Conc. mg/mL);25.72(Max Conc. mM)
??? ??
??
??
Light yellow to light brown
???? ??
Streptomyces griseus
???
13.47g/L(21 ºC)

??

WGK ?? WGK 3
???? ??? 11 - Combustible Solids
?? LD50 i.p. in mice: 14 mg/kg (Vining)

????(200MG) C??? ??, ??, ??

??

Candicidin is a macrocyclic heptaene antifungal complex produced by Streptomyces griseus and isolated by Lechevalier and colleagues in 1953. The candicidin complex comprises analogues A, B, C and D, with candicidin D as the major component. Candicidin is active against fungi, in particular Candida albicans, and is used clinically to treat vaginal candidiasis. Like all polyene antifungal metabolites, candicidin acts by binding to ergosterol and disrupting the fungal membrane.

????(200MG) ?? ?? ? ???

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????(200MG) ?? ??

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