ChemicalBook >?? ???? >?? ???>??? ?? ?? ???>??? ???>?? ???>Tak-715

Tak-715

Tak-715 ??? ???

?? ??:: 303162-79-0

???:: Tak-715

???(??):: Tak-715;CS-1566;TAK-715; TAK715;TAK-715, 10 mM in DMSO;TAK 715, p38 MAPK inhibitor;Tak-715 ISO 9001：2015 REACH;N-(4-(2-Ethyl-4-(m-tolyl)thiazol-5-yl)pyridin-2-yl)benzamide;N-[4-[2-Ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide;N-(4-(2-Ethyl-4-(3-methylphenyl)-thiazol-5-yl)pyridin-2-yl)benzamide;N-(4-(2-Ethyl-4-(3-methylphenyl)-1,3-thiazol-5-yl)-2-pyridyl)benzamide

CBNumber:: CB71017172

???:: C24H21N3OS

??? ??:: 399.51

MOL ??:: 303162-79-0.mol

MSDS ??:: SDS

?? ?? 149

Tak-715 ??

?? ??: Sealed in dry,2-8°C

???: DMSO: >15mg/mL

??? ??: ??

??: ??? ????? ??? ?????

InChI: InChI=1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28)

InChIKey: HEKAIDKUDLCBRU-UHFFFAOYSA-N

SMILES: C(NC1=NC=CC(C2SC(CC)=NC=2C2=CC=CC(C)=C2)=C1)(=O)C1=CC=CC=C1

?? ? ?? ??
?? ? ???? ?? (GHS)

??? ??	Xn
?? ???? ??	22-36
?????	26
WGK ??	3
HS ??	2934999090
???? ???	11 - Combustible Solids
Hazard Classifications	Acute Tox. 4 Oral Eye Irrit. 2

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??		P264, P270, P301+P312, P330, P501
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??		P264, P280, P305+P351+P338,P337+P313P

??????:

P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P280	????/???/???/?????? ?????.
P301+P312	??? ???? ??? ????(??)? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P337+P313	?? ?? ??? ???? ???? ??· ??? ????.

NFPA 704

	0
2		0

Tak-715 C??? ??, ??, ??

??

TAK 715 is a p38 MAPK inhibitor for p38α and p38β but not for p38γ and p38δ.

Tak-715 ?? ?? ? ???

???

(2-methylaziridin-1-yl)-(3-methylphenyl)methanone tert-butyl (4-(2-oxo-2-(M-tolyl)ethyl)pyridin-2-yl)carbaMate 4-(2-ethyl-4-(M-tolyl)thiazol-5-yl)pyridin-2-aMine (4-??-???-2-YL)-????TERT-?????? ?????

?? ??

Tak-715 ?? ??

???( 149)?? ??

???	??	???	??	?? ?	??
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Tak-715 ?? ??:

2-Aminoethyl(ethyl)amine N-ethyl-pyrrolidone N-(2-Hydroxyethyl)-2-pyrrolidone Saracatinib SB 202190 Bardoxolone Methyl SB 203580 VX 702 PH-797804 TAK-020 TAK-659 (hydrochloride) N-Des(aMinocarbonyl) AZ-TAK1 Inhibitor

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