Pirarubicin
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Pirarubicin ??
- ???
- 188-192°C (dec.)
- ??
- D25 +175 ±25° (c = 0.2 in CHCl3)
- ?? ?
- 834.7±65.0 °C(Predicted)
- ??
- 1.51±0.1 g/cm3(Predicted)
- ?? ??
- 2-8°C
- ???
- ???: ???25mg/mL
- ??? ??
- ??
- ?? ?? (pKa)
- 7.35±0.60(Predicted)
- ??
- ????? ?????
- ???
- ???
- InChIKey
- KMSKQZKKOZQFFG-YXRRJAAWSA-N
- SMILES
- C1=C(OC)C2C(=O)C3=C(O)C4[C@@H](O[C@@H]5O[C@@H](C)[C@@H](O[C@H]6OCCCC6)[C@@H](N)C5)C[C@](O)(C(CO)=O)CC=4C(O)=C3C(=O)C=2C=C1
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 36/37/38 | ||
| ????? | 26-37/39 | ||
| WGK ?? | 3 | ||
| RTECS ?? | QI9296000 | ||
| ?? | LD50 i.v. in mice: 27.8 mg/kg (Umezawa, 1979) |
| ????(GHS): |
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| ?? ?: | Danger | |||||||||||||||||||||
| ??·?? ??: |
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| ??????: |
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Pirarubicin C??? ??, ??, ??
??
Pirarubicin is a new anthracycline anticancer agent structurally related to doxorubicin. In acute leukemia, non-Hodgkin’s lymphoma, breast and ovariail carcinoma, pirarubicin is reportedly superior to doxorubicin and better tolerated. Its major side-effect appears to be myelosuppression, mainly in the form of leucopenia, which is potentially dose-limiting.??? ??
Red SolidPirarubicin ?? ?? ? ???
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Pirarubicin ?? ??
???( 295)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 |
Sibel@chuanghaibio.com | China | 8738 | 58 |
| BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD. | +86-18600796368 |
sales@sjar-tech.com | China | 529 | 58 |
| Moxin Chemicals | +86-17320513646 +8617320513646 |
anna@molcoo.com | China | 10000 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 33024 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29815 | 58 |
| Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 965 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-86-5926051114 +8615060885618 |
sales@amoychem.com | China | 6366 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 |
faith@widelychemical.com | CHINA | 742 | 58 |
| Beijing Yibai Biotechnology Co., Ltd | 0086-182-6772-3597 |
sales04@yibaibiotech.com | CHINA | 419 | 58 |
| Jurong Coupling Biotechnology Co., Ltd. | 13656108824 |
coupling278191416@hotmail.com | CHINA | 184 | 58 |
Pirarubicin ?? ??:
?????? 1,8-?????????? 2-(??????)?????
1,2,3,4-TETRAHYDRO-1,5-NAPHTHALENEDIOL
Pirarubicin
Doxorubicinone
Chrysophanic acid
Idarubicin hydrochloride
2-METHOXY-4'-METHYLBENZOPHENONE
2-METHOXY-3'-METHYLBENZOPHENONE
14-Hydroxy Carminomycin
L-DaunosamineHCl
3-METHOXY-3'-METHYLBENZOPHENONE
ISLANDICIN
3-METHOXY-4'-METHYLBENZOPHENONE
2,4-DIMETHYL-3'-METHOXYBENZOPHENONE
4-ETHYL-2'-METHOXYBENZOPHENONE
3,4-DIMETHYL-3'-METHOXYBENZOPHENONE