Ethyl 2-chloro-2-(hydroxyimino)acetate has been used:
in the preparation of (+)-and ()-Δ2-isoxazolines
in the synthesis of CIP-AS (), a chiral amino acid structurally related to glutamic acid, potential agonist at the ionotropic (±±)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid (AMPA)-kainate receptors
to generate ethoxycarbonylformonitrile oxide, in situ by treatment with sodium bicarbonate
to prepare N-azirdinyloximes which on treatment with scandium triflate (418218) provide dihydro-oxadiazines