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2,6-Dichloro-3-nitropyridine

2,6-Dichloro-3-nitropyridine ??? ???
?? ??:
16013-85-7
???:
2,6-Dichloro-3-nitropyridine
???(??):
6-Dichloro-3-nitropyridine;PYRIDINE, 2,6-DICHLORO-3-NITRO-;26DC3NP;TIMTEC-BB SBB003614;2,6-Dichloro-3-nitro;Dichloro-3-nitropyrid;DICHLORONITROPYRIDINE;Flupirtine Impurity H;2,6-DICHLORO-3-NITROPYRIDINE;2,6-Dichloro-3-nitropyrid...
CBNumber:
CB8130660
???:
C5H2Cl2N2O2
??? ??:
192.99
MOL ??:
16013-85-7.mol
MSDS ??:
SDS

2,6-Dichloro-3-nitropyridine ??

???
55-60 °C(lit.)
?? ?
295.5±35.0 °C(Predicted)
??
1.6791 (rough estimate)
???
1.6100 (estimate)
???
>230 °F
?? ??
Keep in dark place,Sealed in dry,Room Temperature
???
???? ???
??? ??
??
?? ?? (pKa)
-5.76±0.10(Predicted)
??
????~???
BRN
1619741
InChI
InChI=1S/C5H2Cl2N2O2/c6-4-2-1-3(9(10)11)5(7)8-4/h1-2H
InChIKey
SHCWQWRTKPNTEM-UHFFFAOYSA-N
SMILES
C1(Cl)=NC(Cl)=CC=C1[N+]([O-])=O
CAS ??????
16013-85-7(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn,Xi
?? ???? ?? 36/37/38-42/43-43
????? 22-26-36/37-37/39-24-36/37/39
WGK ?? 3
?? ?? IRRITANT
HS ?? 29333990
???? ??? 11 - Combustible Solids
Hazard Classifications Eye Irrit. 2
Skin Irrit. 2
Skin Sens. 1
STOT SE 3
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H317 ????? ?? ??? ??? ? ?? ?? ??? ?? ?? 1 ?? P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

2,6-Dichloro-3-nitropyridine MSDS


2,6-Dichloro-3-nitropyridine

2,6-Dichloro-3-nitropyridine C??? ??, ??, ??

??? ??

yellow crystalline powder or chunks

??

2,6-Dichloro-3-nitropyridine was used:

??

2,6-Dichloro-3-nitropyridine is a starting compound for the synthesis of a sulfide analog of Flupirtine with KV7.2/3 channel opening activity. 2,6-Dichloro-3-nitropyridine can be used in pain research.

?? ??

2,6-Dichloro-3-nitropyridine undergoes macrocyclic condensation reaction with resorcinol derivatives to yield chiral tetraoxacalix[2]arene[2]pyridines.

Structure and conformation

The asymmetric unit of 2,6-Dichloro-3-nitropyridine consists of two crystallographically independent mol-ecules. The pyridine ring in each mol-ecule is essentially planar, with maximum deviations of 0.004 (4) and 0.007 (4)Å. Short Cl-O [3.09(3) and 3.13 (4)Å] and Cl-Cl [3.38 (12)Å] contacts were observed. No significant inter-molecular inter-actions were observed in the crystal packing.
2,6-Dichloro-3-nitropyridine

2,6-Dichloro-3-nitropyridine ?? ?? ? ???

???

?? ??


2,6-Dichloro-3-nitropyridine ?? ??

???( 610)?? ??
??? ?? ??? ?? ?? ? ??
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2,6-Dichloro-3-nitropyridine ?? ??:

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