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2-?????

2-?????
2-????? ??? ???
?? ??:
6872-06-6
???:
2-?????
???(??):
2-?????
???:
2-Methylindoline
???(??):
2,3-Dihydro-2-methyl-1H-indole;PE-11;NSC 65598;2-methyl-indolin;2-METHYLINDOLINE;Indoline, 2-methyl-;2-Methylindoline>2-Methyl-1H-indoline;α-Methyldihydroindole;a-Methyldihydroindole
CBNumber:
CB8169273
???:
C9H11N
??? ??:
133.19
MOL ??:
6872-06-6.mol

2-????? ??

???
-51 °C
?? ?
228-229 °C (lit.)
??
1.023 g/mL at 25 °C (lit.)
???
n20/D 1.569(lit.)
???
200 °F
?? ??
Keep in dark place,Inert atmosphere,Room temperature
???
?????, ???? ???
?? ?? (pKa)
5.26±0.40(Predicted)
??? ??
??
Specific Gravity
1.02
??
??? ????? ????
?? ??
-2.4550° (C=1.0 g/100ml, MEOH, 20°C, 589nm)
???
??? ??
InChI
1S/C9H11N/c1-7-6-8-4-2-3-5-9(8)10-7/h2-5,7,10H,6H2,1H3
InChIKey
QRWRJDVVXAXGBT-UHFFFAOYSA-N
SMILES
CC1Cc2ccccc2N1
CAS ??????
6872-06-6(CAS DataBase Reference)
NIST
2-Methylindoline(6872-06-6)
EPA
1H-Indole, 2,3-dihydro-2-methyl- (6872-06-6)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi,Xn
?? ???? ?? 36/37/38-52/53-22
????? 26-36/37/39-60-57
WGK ?? 3
RTECS ?? NM1926350
?? ?? ?? Irritant
TSCA TSCA listed
HS ?? 29349990
???? ??? 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Dermal
Acute Tox. 4 Oral
Aquatic Acute 1
Eye Irrit. 2
????(GHS): Skull and Crossbones (GHS06)Environment (GHS09)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H311 ??? ???? ??? ?? ?? ?? - ?? ?? 3 ?? P280, P302+P352, P312, P322, P361,P363, P405, P501
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H400 ????? ?? ??? ?? ????? ?? - ?? ?? 1 ?? P273, P391, P501
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P273 ???? ???? ???.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
2 0

2-????? MSDS


2-Methylindoline

2-????? C??? ??, ??, ??

??? ??

CLEAR YELLOW TO BROWN LIQUID

??

2-Methylindoline is an intermediate in the production of various indole derivatives

?? ??

2-Methylindoline is prepared through the transformation of 1-(2-aminophenyl)propan-2-ol using acidic catalysts[1]. 2-Methylindoline is also produced by the hydrogenation of 2-methylindole in toluene[2].

Synthesis Reference(s)

Journal of the American Chemical Society, 111, p. 4108, 1989 DOI: 10.1021/ja00193a056
Chemical and Pharmaceutical Bulletin, 26, p. 108, 1978 DOI: 10.1248/cpb.26.108

2-????? ?? ?? ? ???

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2-????? ?? ??

???( 318)?? ??
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2-????? ?? ??:

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