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Mirin

Mirin ??? ???

?? ??:: 1198097-97-0

???:: Mirin

???(??):: CS-2593;(Z)-Mirin;(Z)-Mirin, 10 mM in DMSO;(Z)-Mirin,Inhibitor,(Z)Mirin,(Z) Mirin,inhibit;(Z)-2-Amino-5-(4-hydroxybenzylidene)thiazol-4(5H)-one;(5Z)-2-Amino-5-[(4-hydroxyphenyl)methylene]-4(5H)-thiazolone;4(5H)-Thiazolone, 2-amino-5-[(4-hydroxyphenyl)methylene]-, (5Z)-;(5Z) -2-amino-5- [(4-hydroxyphenyl) methylene] -4 (5H) - thiazolidone

CBNumber:: CB83037397

???:: C10H8N2O2S

??? ??:: 220.25

MOL ??:: 1198097-97-0.mol

?? ?? 110

Mirin ??

?? ?: 441.6±55.0 °C(Predicted)

??: 1.49±0.1 g/cm3(Predicted)

?? ??: Store at -20°C

???: insoluble in EtOH; insoluble in H2O; ≥9.3 mg/mL in DMSO

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 8.70±0.30(Predicted)

??: Light yellow to yellow

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	?? ??	P- ??
H315	??? ??? ???	????? ?? ?????	?? 2	??		P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??		P264, P280, P305+P351+P338,P337+P313P

??????:

P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P280	????/???/???/?????? ?????.
P302+P352	??? ??? ??? ?? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321	(…) ??? ???.
P332+P313	?? ??? ??? ???? ??· ??? ????.
P362	??? ??? ?? ?? ?? ?????

Mirin C??? ??, ??, ??

??

Mirin is an MRN-ATM pathway inhibitor blocking 3’ and 5’ exonuclease activity associated with Mre11, inducing G2 cell cycle arrest.

Mirin ?? ?? ? ???

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4-HYDROXYBENZYLIDENEMALONONITRILE ?????????? 4-??????????

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Mirin ?? ??

???( 110)?? ??

???	??	???	??	?? ?	??
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Mirin ?? ??:

Phenol 5-[[4-(4-Pyridinyl)-6-quinolinyl]methylene]-2,4-thiazolidenedione (5Z)-5-[[3-(Trifluoromethyl)phenyl]methylene]-2,4-thiazolidinedione

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