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592-88-1
???:
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???(??):
??????;??????
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Diallyl sulfide
???(??):
ALLYL SULFIDE;Oil garlic;FEMA 2042;DIALLYL SULPHIDE;ALLYL SULPHIDE;Allyl monosulfide;di-2-propenyl sulfide;Diallyl sulfide, 97% / Allyl sulfide;NSC 20947;oilgarlic
CBNumber:
CB8356893
???:
C6H10S
??? ??:
114.21
MOL ??:
592-88-1.mol
MSDS ??:
SDS

?? ???? ??

???
-83 °C
?? ?
138 °C(lit.)
??
0.887 g/mL at 25 °C(lit.)
?? ??
3.9 (vs air)
???
7 mm Hg ( 20 °C)
???
n20/D 1.490(lit.)
FEMA
2042 | ALLYL SULFIDE
???
115 °F
?? ??
2-8°C
???
3mg/mL in ethanol;5mg/mL in DMSO;10mg/mL in dimethyl formamide
??? ??
??
??
???
??
???? ??? ? 0.10%. ?? ?? ?? ? ?? ?? ???
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???
???? ??
synthetic
Odor Threshold
0.00022ppm
????
1.1%(V)
???
???, ?????, ??? ? ?????? ?????. ?? ???.
Merck
14,297
JECFA Number
458
BRN
1736016
Henry's Law Constant
4.1×10-3 mol/(m3Pa) at 25℃, Lindinger et al. (1998)
Dielectric constant
4.9(20℃)
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?? ? ?
??? ?? ??
??
InChI
1S/C6H10S/c1-3-5-7-6-4-2/h3-4H,1-2,5-6H2
InChIKey
UBJVUCKUDDKUJF-UHFFFAOYSA-N
SMILES
C=CCSCC=C
LogP
2.61
CAS ??????
592-88-1(CAS DataBase Reference)
NIST
1-Propene, 3,3'-thiobis-(592-88-1)
EPA
1-Propene, 3,3'-thiobis- (592-88-1)
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  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 10-36/37/38
????? 26-36-37/39-23-16
????(UN No.) UN 1993 3/PG 3
WGK ?? 2
RTECS ?? BC4900000
TSCA TSCA listed
?? ?? 3
???? III
HS ?? 29309070
???? ??? 3 - Flammable liquids
Hazard Classifications Flam. Liq. 3
?? ?? ??? 592-88-1(Hazardous Substances Data)
???? ?? KE-33777
????(GHS): Flame (GHS02)Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H226 ??? ?? ? ?? ??? ?? ?? 3 ??
H303 ??? ??? ? ?? ?? ?? ?? - ?? ?? 5 P312
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
??????:
P210 ?·???·??·????? ????? - ?? ???.
P233 ??? ??? ?????. ??? ??? ? ?? ?? ??? ???? ?????.
P240 ??? ????? ?? ? ??????.
P241 ?? ??? ??[???/??/??/...]?(?) ?????.
P242 ???? ???? ?? ??? ?????
P243 ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P312 ???? ??? ????(??)? ??? ????.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
P370+P378 ?? ? ?? ?? ?? (Section 5. ??, ??? ????? ??? ???)?(?) ?????.
P403+P235 ??? ? ?? ?? ???? ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
2
2 0

?? ???? MSDS


Allyl sulfide

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clear colorless liquid

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Reported found in garlic (Allium sativum L.), onion (Allium cepa L.), nira (Allium tuberosum Rottl.), caucas (Allium victoralis L.), mustard (Brassica species) and cooked/boiled beef

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Diallyl sulfide is a modulator of drug metabolizing enzyme P450 system and inducer of the phase II detoxifying enzyme GST. Diallyl sulfide is also an inhibitor of CYP2E1 and believed to prevent chemically-induced carcinogenesis in many tissues. It is also used as a food additive. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

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From allyl iodide plus potassium sulfide in alcoho

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Allyl sulfide is a volatile flavor compound naturally found in Allium species such as garlic and onion. It is has a characteristic garlic odor and is used as a flavoring agent in meat and condiments.

Anticancer Research

It is a thioether, found in garlic, inhibits cytochrome P450 IIE1 isoform, and therebysuppresses carcinogenesis (Aggarwal and Shishodia 2004). The consumption ofgarlic provides protection from gastrointestinal cancers and also suppresses theprogression of colorectal adenomas (Hosseini and Ghorbani 2015).

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