????? ???
|
|
????? ??? ??
- ???
- 230 °C (lit.)
- ??
- 1.3265 (rough estimate)
- ???
- 1.5430 (estimate)
- ?? ??
- Inert atmosphere,Room Temperature
- ???
- ???(??), ?(??)? ???
- ?? ?? (pKa)
- pKa 7.8-8 (Uncertain)
- ??? ??
- ??
- ??? ??
- ??? ??
- ??
- ???? ?????
- ???? ??
- synthetic (organic)
- ???
- 65.5g/100mL(25℃)
- Merck
- 14,7703
- BRN
- 4163981
- InChI
- InChI=1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H
- InChIKey
- HIGSLXSBYYMVKI-UHFFFAOYSA-N
- SMILES
- C1(/C=N/O)C=CC=C[N+]=1C.[Cl-]
- CAS ??????
- 51-15-0(CAS DataBase Reference)
??
- ?? ? ?? ??
| ??? ?? | Xn | ||
|---|---|---|---|
| ?? ???? ?? | 20/21/22-36/37/38-20/22 | ||
| ????? | 36-37/39-26 | ||
| WGK ?? | 3 | ||
| RTECS ?? | UU4200000 | ||
| HS ?? | 29333999 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Acute Tox. 4 Dermal Acute Tox. 4 Inhalation Acute Tox. 4 Oral |
||
| ?? | LD50 in rats (mg/kg): 96 i.v. (Fleisher); LD50 in rabbits (mg/kg): 95 i.v.; LD50 in mice (mg/kg): 115 i.v., 205 i.p., 4100 orally (Ellin, Wills) | ||
| ???? ?? | KE-20591 |
????? ??? C??? ??, ??, ??
??? ??
white to off-white adhering crystalline powder??
This compound binds to inactivated acetylcholinesterases and is used to combat poisoning from organophosphates and nerve agents?? ??
Pralidoxime chloride, 2-formyl-1-methylpyridinium chloride oxime, 2-PAM chloride,or 2-pyridine aldoxime methyl chloride (Protopamchloride), is a white, nonhygroscopic, crystalline powderthat is soluble in water, 1 g in less than 1 mL.Clinical Use
Pralidoxime chloride is used as an antidote for poisoningby parathion and related pesticides. It may be effectiveagainst some phosphates that have a quaternary nitrogen. Itis also an effective antagonist for some carbamates, such asneostigmine methylsulfate and pyridostigmine bromide.????? ??? ?? ?? ? ???
???
?? ??
????? ??? ?? ??
???( 340)?? ??
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