?????????
|
|
????????? ??
- ???
- 86-89 °C (lit.)
- ?? ?
- 206-210 °C (lit.)
- ??
- 1.0125 (rough estimate)
- ???
- 1.78Pa at 20℃
- ???
- 1.4860 (estimate)
- ???
- 90 °C
- ?? ??
- Store below +30°C.
- ???
- 17.7g/L
- ??? ??
- ??? ??, ?? ?? ???
- ?? ?? (pKa)
- 12.42±0.20(Predicted)
- ??
- ????? ???? ????
- ???
- 20°C?? <0.1g/100mL
- BRN
- 1616769
- Henry's Law Constant
- 4.3×101 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
- Dielectric constant
- 3.0（89℃）
- ???
- ????. ?? ??. ?? ???? ???? ????. ???? ????? ???? ???.
- InChI
- 1S/C6H11NO/c8-7-6-4-2-1-3-5-6/h8H,1-5H2
- InChIKey
- VEZUQRBDRNJBJY-UHFFFAOYSA-N
- SMILES
- O\N=C1/CCCCC1
- LogP
- 1.265 at 25℃
- CAS ??????
- 100-64-1(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xn | ||
|---|---|---|---|
| ?? ???? ?? | 22 | ||
| ????? | 36/37/39 | ||
| WGK ?? | 1 | ||
| RTECS ?? | GW1925000 | ||
| TSCA | TSCA listed | ||
| HS ?? | 29280090 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Acute Tox. 4 Oral | ||
| ?? ?? ??? | 100-64-1(Hazardous Substances Data) |
????????? C??? ??, ??, ??
??? ??
Cyclohexanone oxime, a white crystalline solid, has a molecular weight of 113.16 and a melting point of 90 C. It is soluble in water and ethanol (Lide, 1992). This colorless solid is an important intermediate in the production of nylon 6, a widely used polymer. Cyclohexanone oxime is produced by the condensation of cyclohexanone with hydroxylamine sulfate or hydroxylamine phosphate (Fisher and Cresentini, 1985).??
Cyclohexanone oxime is used in a wide variety of industrial applications. Primarily, it is used as a captive intermediate in the synthesis of caprolactam, which is polymerized in the production of polycaprolactam (Nylon-6) fibers and plastics (Fisher and Cresentini, 1985; NCI, 1985). The annual U.S. caprolactam production is over 500,000 tons (NCI, 1985). Approximately 90% of the monomer is used to produce fibers for clothing, carpets, home furnishings, and tire cording. The remaining 10% is used to produce nylon resins for food packaging film, extrusion compounds for bristle filaments and wire coatings, and molded plastics for automobiles and appliances (NCI, 1985). Cyclohexanone oxime is also thought to be an intermediate in the oxidative metabolism of sodium cyclamate, an artificial sweetener (Unger and McMahon, 1981).?? ??
Prisms, liquid or light tan crystalline solid.??? ?? ??
Insoluble in water.?? ???
Cyclohexanone oxime reacts violently with fuming sulfuric acid at temperatures > 302° F. . Several explosions or violent decompositions have occurred during distillation of aldooximes, which may be attributable to the formation of peroxides of various types. This is especially the case in the presence of acid, Chem. Eng. News, 1974, 52(35), 3. A nickel catalyzed aldoxime rearrangement to an amide, went out of control after changing the solvent employed, J. Loss Prev., 1993, 6(2), 69.????
ACUTE/CHRONIC HAZARDS: When heated to decomposition Cyclohexanone oxime emits toxic fumes of nitrogen oxides.????
Flash point data for Cyclohexanone oxime are not available; however, Cyclohexanone oxime is probably combustible.Purification Methods
Crystallise the oxime from water or pet ether (b 60-80o). [Bousquet Org Synth Coll Vol II 313 1943, Beilstein 7 III 32, 7 IV 21.]????????? ?? ?? ? ???
???
?????
Cyclohexanimine
????(???????)??
2H-Pyran, 2-(cyclohexyloxy)tetrahydro-
1-Amino-1-hydroperoxycyclohexane
N-CYCLOHEXYLHYDROXYLAMINE
Cyclohexanone, 2-cyclohexylidenehydrazone
???????????
??????
?? ??
????????? ?? ??
???( 389)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 |
faithe@yan-xi.com | China | 5853 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21586 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29815 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49979 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 |
joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23541 | 58 |
| Baoji Guokang Healthchem Co., Ltd. | +86-0917-3909592 +86-13892490616 |
gksales1@gk-bio.com | China | 9067 | 58 |
| CD Chemical Group Limited | +8615986615575 |
info@codchem.com | China | 17259 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 |
2571773637@qq.com | China | 9653 | 58 |
????????? ?? ??:
??????? ????? ??????? ?????????
(1S,E)-(-)-Camphorquinone 3-oxime
1,2-CYCLOHEXANEDIONE DIOXIME
2-Adamantanone oxime
ANTIOXIDANT
4-Methylcyclohexanoneoxime
OXIME
1,2,3-CYCLOHEXANE TRIONE-1,3-DIOXIME
ANTI-(1R)-(+)-CAMPHORQUINONE 3-OXIME
4-HYDROXYIMINO-2,2-DIMETHYL-4,5,6,7-TETRAHYDRO-2H-BENZO[D]IMIDAZOL-1-IUM-1-OLATE
1,7,7-TRIMETHYLBICYCLO[2.2.1]HEPTAN-2-ONE OXIME
DIMEDONE DIOXIME
4-(TERT-BUTYL)CYCLOHEXANONE OXIME
MILBEMYCIN OXIME
2-[(([4-(TERT-BUTYL)CYCLOHEXYLIDEN]AMINO)OXY)CARBONYL]THIOPHENE
1-[(([4-(TERT-BUTYL)CYCLOHEXYLIDEN]AMINO)OXY)CARBONYL]-4-METHYLBENZENE