Primaxin monohydrate
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Primaxin monohydrate ??
- ???
- 193-198°C
- ?? ?
- 567℃
- RTECS ??
- CL5446516
- ???
- >110°(230°F)
- ?? ??
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- ???
- H2O: >5mg/mL
- ?? ?? (pKa)
- pKa 3.2/9.9(H2O,t = 25) (Uncertain)
- ??? ??
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- [α]/D +73 to +84°, c =0.5 in water
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- 5mg/ml? ?? ???
- InChI
- InChI=1/C12H17N3O4S.H2O/c1-6(16)9-7-4-8(20-3-2-14-5-13)10(12(18)19)15(7)11(9)17;/h5-7,9,16H,2-4H2,1H3,(H2,13,14)(H,18,19);1H2/t6-,7-,9-;/s3
- InChIKey
- GSOSVVULSKVSLQ-ONZDYIGBNA-N
- SMILES
- C(C1=C(C[C@]2([H])[C@@]([H])([C@H](O)C)C(=O)N12)SCCNC=N)(=O)O.O |&1:4,6,8,r|
- CAS ??????
- 74431-23-5(CAS DataBase Reference)
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- ?? ? ???? ?? (GHS)
| WGK ?? | 3 | ||
|---|---|---|---|
| HS ?? | 2941906000 | ||
| ???? ??? | 11 - Combustible Solids |
| ????(GHS): |
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| ?? ?: | Warning | |||||||||||||||||||||
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Primaxin monohydrate C??? ??, ??, ??
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Off-White Solid??
Imipenem has a broad spectrum of antimicrobial action, which includes most clinically significant microorganisms: Gram-positive, Gram-negative, aerobic, and anaerobic. It is resistant with respect to most beta-lactamases of Gram-positive and Gram-negative bacteria. It is used for bacterial infections of the lower respiratory tract, infections of the urinary and sexual tracts, infections of bones, joints, skin, soft tissues, intraabdominal and gynecological infections, bacterial septicemia, and endocarditis.Imipenem undergoes enzymatic inactivation in the kidneys. In order to avoid this problem, it is used in a 1:1 ratio in combination with cilastatin—the sodium salt of [R-[R,S-(Z)]]-7-[(2- amino-2-carboxyethyl)thio]-2-[[(2,2-dimethylcyclopropyl)aminocarbonyl-2-heptenoic acid (32.1.3.6), which inhibits metabolisms of imipenem in the kidneys. This combination of two compounds is also used in medicine under the name primaxin.
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Chemical structure: -lactamPrimaxin monohydrate ?? ?? ? ???
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INSTANT BUFFER S70, PH7.0 (ACC. TO SOERENSEN)(50PACKS)
Trimethacrylate
Benzyl ester
N,N-?????????
Sodium bisulfite water solution
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Primaxin monohydrate ?? ??
???( 328)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8618531123677 |
faithe@yan-xi.com | China | 5853 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +8618092446649 |
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| Apeloa production Co.,Limited | +8619933239880 |
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| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
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| Speranza Chemical Co., Ltd. | +86-86-075521030354 +8618688942810 |
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| career henan chemical co | +86-0371-86658258 +8613203830695 |
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| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49979 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 |
1056@dideu.com | China | 3970 | 58 |
Primaxin monohydrate ?? ??:
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Glucosamine
2-(METHYLSULFONYL)ETHANOL
(5R,6S)-3-[(Diphenoxyphosphinyl)oxy]-6-[(1R)-1-hydroxyethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (4-nitrophenyl)methyl ester
INTERMEDIANTE FOR IMIPENEM
Imipenem