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4-chloro-6,7-dimethoxyquinoline

4-chloro-6,7-dimethoxyquinoline ??? ???
?? ??:
35654-56-9
???:
4-chloro-6,7-dimethoxyquinoline
???(??):
4-Chloro-6,7-dimethoxyquioline;6,7-DIMETHOXY-4-CHLOROQUINOLINE;4-CHLORO-6;7-DIMETHOXYQUINOLINE;oro-6,7-dimethoxyquinoL;Cabozantinib Impurity 71;Cabozantinib Chloro Analog;4-CHLORO-6,7-DIMETHOXYQUINOLINE;4-Chloro-6,7-dimethoxy-quinolin;Quinoline, 4-chloro-6,7-dimethoxy-
CBNumber:
CB8725015
???:
C11H10ClNO2
??? ??:
223.66
MOL ??:
35654-56-9.mol

4-chloro-6,7-dimethoxyquinoline ??

???
132.0 to 136.0 °C
?? ?
325.2±37.0 °C(Predicted)
??
1.265±0.06 g/cm3(Predicted)
?? ??
Keep in dark place,Sealed in dry,Room Temperature
???
DMSO(?? ???), ???(?? ???)
??? ??
??
??? ??
??? ??
?? ?? (pKa)
3.95±0.30(Predicted)
??
?? ???? ?? ????
InChI
InChI=1S/C11H10ClNO2/c1-14-10-5-7-8(12)3-4-13-9(7)6-11(10)15-2/h3-6H,1-2H3
InChIKey
WRVHQEYBCDPZEU-UHFFFAOYSA-N
SMILES
N1C2C(=CC(OC)=C(OC)C=2)C(Cl)=CC=1
CAS ??????
35654-56-9(CAS DataBase Reference)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? T
?? ???? ?? 25
????? 45-24/25
????(UN No.) UN2811
WGK ?? WGK 3
?? ?? IRRITANT
HS ?? 29334900
???? ??? 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
Hazard Classifications Acute Tox. 3 Oral
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P280 ????/???/???/?????? ?????.
P302+P352 ??? ??? ??? ?? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P321 (…) ??? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P362 ??? ??? ?? ?? ?? ?????
NFPA 704
0
1 0

4-chloro-6,7-dimethoxyquinoline C??? ??, ??, ??

??? ??

Light brown powder

??

4-Chloro-6,7-dimethoxyquinoline, can be used as an intermediate for the synthesis of various pharmaceutical and biologically active compounds. It is used for the preparation of Tivozanib (T447205), and Cabozantinib (C051500), acting as anticancer agents.

?? ??

4-chloro-6,7-dimethoxy-quinoline can be rich for Buddhist nun with for Wo Zhani medicine as preparing antitumor drug card The key intermediate of thing molecule synthesis.

4-chloro-6,7-dimethoxyquinoline ?? ?? ? ???

???

?? ??


4-chloro-6,7-dimethoxyquinoline ?? ??

???( 409)?? ??
??? ?? ??? ?? ?? ? ??
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4-chloro-6,7-dimethoxyquinoline ?? ??:

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