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?????? ??? ???
?? ??:
503-74-2
???:
??????
???(??):
??????;??????;??????(ISOPENTANOICACID);??????
???:
Isovaleric acid
???(??):
3-METHYLBUTANOIC ACID;3-METHYLBUTYRIC ACID;ISOPENTANOIC ACID;Butanoicacid,3-methyl-;FEMA 3102;isopentanoic;Isoamyl Acid;3-methylbutyrate;Isovalerianic acid;3-Methybutyric Acid
CBNumber:
CB8729604
???:
C5H10O2
??? ??:
102.13
MOL ??:
503-74-2.mol
MSDS ??:
SDS

?????? ??

???
-29 °C (lit.)
?? ?
175-177 °C (lit.)
??
0.925 g/mL at 20 °C (lit.)
???
0.38 mm Hg ( 20 °C)
FEMA
3102 | ISOVALERIC ACID
???
n20/D 1.403(lit.)
???
159 °F
?? ??
Store below +30°C.
???
48g/L
??? ??
??
?? ?? (pKa)
4.77(at 25℃)
??
????~???
Specific Gravity
0.928 (20/20℃)
??
???? ??? ? 1.00%. ? ?? ?? ? ?? ?? ?? ??
??????(pH)
3.92(1 mM solution);3.4(10 mM solution);2.89(100 mM solution);
????
1.5-6.8%(V)
?? ??
???? ??
???? ??
synthetic
???
25g/L(20℃)
Merck
14,5231
JECFA Number
259
BRN
1098522
Henry's Law Constant
2.7×101 mol/(m3Pa) at 25℃, Kim and Kim (2016)
Dielectric constant
2.6(20℃)
?? ??
flavors and fragrances
??? ?? ??
PERFUMING
InChI
1S/C5H10O2/c1-4(2)3-5(6)7/h4H,3H2,1-2H3,(H,6,7)
InChIKey
GWYFCOCPABKNJV-UHFFFAOYSA-N
SMILES
CC(C)CC(O)=O
LogP
1.7 at 25℃
CAS ??????
503-74-2(CAS DataBase Reference)
NIST
Butanoic acid, 3-methyl-(503-74-2)
EPA
Isovaleric acid (503-74-2)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? C,T
?? ???? ?? 34-24-22
????? 26-36/37/39-45-38-28A
????(UN No.) UN 3265 8/PG 2
WGK ?? 1
RTECS ?? NY1400000
F ?????? 13
?? ?? ?? 824 °F
TSCA TSCA listed
HS ?? 2915 60 90
?? ?? 6.1
???? III
???? ??? 8A - Combustible corrosive hazardous materials
Hazard Classifications Eye Dam. 1
Skin Corr. 1B
?? ?? ??? 503-74-2(Hazardous Substances Data)
?? LD50 i.v. in mice: 1120±30 mg/kg (Or, Wretlind)
???? ?? KE-23545
????(GHS): Corrosion (GHS05)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H314 ??? ?? ??? ?? ??? ??? ????? ?? ????? ?? 1A, B, C ?? P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
??????:
P280 ????/???/???/?????? ?????.
P301+P330+P331 ???? ?? ?????. ??? ?? ?? ???.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P363 ?? ??? ??? ??? ?????.
NFPA 704
2
3 0

?????? C??? ??, ??, ??

??

Isovaleric acid has a characteristic disagreeable odor. It is extremely penetrating and persistent with a sour taste. May be synthesized by oxidation of isoamyl alcohol or isovaleric aldehyde.

??? ??

Isovaleric acid has a characteristic disagreeable, rancid, cheese-like odor. It is extremely penetrating and persistent with a sour taste. May consist of one or a mixture of isomers or n-pentanoic acid and/or 2- or 3-methyl butanoic acid. Consumption: Annual: 1850.00 lb

??

Of the three possible isomers of n-valeric acid, only isovaleric acid has extensive application in flavoring; originally reported in seal and dolphin fat; subsequently isolated from valerian. Also reported found in the essential oils of cypress, citronella, laurel leaves, cajeput, Cymbopogon javanensis, hops, Persea pubescens, geranium, American peppermint, spearmint, rosemary, lemongrass, Eucalyptus goniocalyx and other spp., tobacco, Monarda fistulos, Thymus mastichina, Artemisia frigida, and probably in lavender; reported among the constituents of petitgrain lemon. Also reported found in many foods including apple, currants, guava, grapes, papaya, peach, pineapple, raspberry, strawberry, potato, bell pepper, vinegar, breads, many cheeses, fish, chicken, lamb, hop oil, beer, cognac, whiskies, cider, sherry, grape wines, rum, cocoa, tea, coffee, honey, soybean, passion fruit, mushrooms, marjoram, plum, brandy, starfruit, trassi, rice, jackfruit, sake, sukiyaki, buckwheat, corn oil, cashew apple, malt, wort, Bourbon vanilla, shrimp, mussels, cherimoya, Cape gooseberry and Chinese quince frui

??

Isovaleric acid is used extensively as a flavoring ingredient in nonalcoholic beverages and in foods such as ice cream, candy, baked goods, and cheese, as a fragrance ingredient in perfumes, and as a chemical intermediate in the manufacture of sedatives and other pharmaceutical products. It is also used as an extractant of mercaptans from petroleum hydrocarbons, a vinyl stabilizer, and as an intermediate in the manufacture of plasticizers and synthetic lubricants.

?? ??

By oxidation of isoamyl alcohol or isovaleric aldehyde

??

ChEBI: A C5, branched-chain saturated fatty acid.

?? ??

Isovaleric acid is a colorless liquid with a penetrating odor. Isovaleric acid is slightly soluble in water. Isovaleric acid is corrosive to metals and to tissue.

??? ?? ??

Isovaleric acid is slightly soluble in water.

???

Strong irritant to tissue.

????

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

????

Non-combustible, substance itself does not burn but may decompose upon heating to produce corrosive and/or toxic fumes. Some are oxidizers and may ignite combustibles (wood, paper, oil, clothing, etc.). Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated.

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