???????????
|
|
??????????? ??
- ?? ?
- 272-275 °C(lit.)
- ??
- 1.087 g/mL at 25 °C(lit.)
- ???
- n
20/D 1.505(lit.)
- ???
- >230 °F
- ?? ??
- 2-8°C
- ??? ??
- ??? ??
- ??
- Colorless to Light orange to Yellow
- ??
- 100.00%??. ??? ?? ?? ? ? ??
- ?? ??
- ?? ??
- ???? ??
- synthetic
- JECFA Number
- 1577
- BRN
- 12299
- ?? ??
- ?? ? ?
- ??? ?? ??
- ?? ??
??
- InChI
- 1S/C12H14O3/c1-3-14-11(13)10-12(2,15-10)9-7-5-4-6-8-9/h4-8,10H,3H2,1-2H3
- InChIKey
- LQKRYVGRPXFFAV-UHFFFAOYSA-N
- SMILES
- CCOC(=O)C1OC1(C)c2ccccc2
- LogP
- 2.43
- CAS ??????
- 77-83-8(CAS DataBase Reference)
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 10-36/37/38 | ||
| ????? | 16-26-36/37/39 | ||
| ????(UN No.) | UN 1993 3/PG 3 | ||
| WGK ?? | 2 | ||
| RTECS ?? | MW5250000 | ||
| TSCA | TSCA listed | ||
| ?? ?? | 3 | ||
| HS ?? | 29189090 | ||
| ???? ??? | 10 - Combustible liquids | ||
| Hazard Classifications | Aquatic Chronic 2 Skin Sens. 1B |
||
| ?? ?? ??? | 77-83-8(Hazardous Substances Data) | ||
| ?? | LD50 orally in Rabbit: 5470 mg/kg | ||
| ???? ?? | KE-13687 |
??????????? C??? ??, ??, ??
??? ??
Ethyl 3-Methyl-3-phenylglycidate exists as two optically active pairs of cis- and trans-isomers; each isomer has a characteristic odor . The commercial product is a racemic mixture of all four isomers and has a strong, sweetish, strawberry odor. The cis/trans ratio obtained in the Darzens condensation of acetophenone (R==CH3) and ethyl chloroacetate depends on the base used in the reaction.??
Has apparently not been reported to occur in nature.??
Ethyl 3-methyl-3-phenylglycidate is a synthetic flavoring agent that is a glycidic acid ester. It is a colorless to pale yellow liquid with a strong fruit odor suggestive of strawberries. It is unstable to alkali and moderately stable to weak organic acids. It should be stored in glass, tin, or aluminum containers. It is soluble in fixed oils and in propylene glycol. It is used in flavors for strawberry note and has application in candy, beverages, and ice cream at 6–20 ppm. It is also termed aldehyde c-16.?? ??
By reaction of acetophenone and the ethyl ester of monochloroacetic acid in the presence of an alkaline condensing agent.?? ??
Clear, colorless to yellowish liquid with a strawberry-like odor.??? ?? ??
Insoluble in water.?? ???
Esters, such as Ethyl 3-methyl-3-phenylglycidate, react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.????
Ethyl 3-methyl-3-phenylglycidate is probably combustible.???
Strawberry pure (Givaudan)Safety Profile
Mddly toxic by ingestion. Mutation data reported. Combustible liquid. When heated to decomposition it emits acrid smoke and irritating fumes. See also ALDEHYDES.Solubility in organics
Poorly soluble in Propylene glycol, Glycerin and mineral oil, soluble in alcohol, miscible with most perfume and flavor oils.??????????? ?? ?? ? ???
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