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??????? ??? ???
?? ??:
527-07-1
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???(??):
D-????,??????;D-????????;PMP????????;????,????;????,??????;????,??????,D-;???????;????????;???D-?????;??????????;??????;D-???????;????????;???????;2,3,4,5,6-??????? ??? ? ??? ?;D-??? ?, ????? ?;D-???? ???;PMP ??? ?????;???;??? ?, ??? ?
???:
Sodium gluconate
???(??):
SODIUM D-GLUCONATE;GLUCONIC ACID SODIUM SALT;glonsen;Natriumgluconat;Gluconic Acid Sodium;SODIUM GLUCONATE REAGENT;sodium pentahydyoxycaproate;pasexon100t;BVD Addicrete;Sunmorl N 60S
CBNumber:
CB9229989
???:
C6H13NaO7
??? ??:
220.15
MOL ??:
527-07-1.mol
MSDS ??:
SDS

??????? ??

???
170-175 °C
??
[α]D20 +11~+13° (c=10, H2O)
?? ??
Store below +30°C.
???
H2O: 0.1 g/mL, ??
??? ??
??? ??
??
??~?? ???
??
??? ????. ??., ?? ?? ??
??????(pH)
7.0-8.0 (100g/l, H2O, 20℃)
???? ??
microbial
???
?? ?? ? ????. ???? ?? ???? ??; ???? ???.
Merck
14,4456
BRN
3919651
???
????. ?? ???? ???? ????.
?? ??
??
??? ?? ??
?? ????
????
InChI
InChI=1/C6H12O7.Na.H/c7-1-2(8)3(9)4(10)5(11)6(12)13;;/h2-5,7-11H,1H2,(H,12,13);;/t2-,3-,4+,5-;;/s3
InChIKey
MPPJUDJABRMYJR-QZHCVFHNNA-N
SMILES
[C@@H](O)([C@@H](O)C(=O)O)[C@H](O)[C@H](O)CO.[NaH] |&1:0,2,7,9,r|
LogP
-3.175 (est)
CAS ??????
527-07-1(CAS DataBase Reference)
EPA
Sodium gluconate (527-07-1)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
????? 24/25
WGK ?? 1
RTECS ?? LZ5235000
?? ?? ?? >200 °C
TSCA TSCA listed
HS ?? 29181600
???? ??? 11 - Combustible Solids
?? LD50 orally in Rabbit: > 2000 mg/kg
???? ?? KE-17676
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P302+P352 ??? ??? ??? ?? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
NFPA 704
1
1 0

??????? MSDS


Gluconic acid sodium salt

??????? C??? ??, ??, ??

????

? (1) ? : ? ?? 5.0g? ??? ??????? ?? ?????????????? ?? ??? ?, ? ?? 2.0ppm ????? ??.

??(2) ???? : ? ?? ? 1g? ??? ?? 250mL ??????? ??? ? 10mL? ??? ???. ? ?? ????????? 25mL? ??? ?? ???? ??? ? ? ??? 5?? ??? ???? ???? ????. ? ?? ??(1→10) 25mL, 0.1N ????? 10mL, ???? 10mL ? ???? 3mL? ??? ??? ??? ??? 0.1N ??????????? ??? ?, ? ?? 0.5% ????? ?? .

V1 : 0.1N ?????? ???(mL)

N1 : 0.1N ?????? ????

V2 : 0.1N ?????????? ???(mL)

N2 : 0.1N ?????????? ????

27 : D-?????? ?? ??? ???

????

? (1) ? ??? ???(1→20)? ????? ? ????? ??? ????.

??(2) ? ??? ??? ???(1→10) 5mL? ??? 0.7mL ? ?? ??? ?????? 1mL? ??? ????? 30?? ???? ?? ??, ????? ??? ?? ? ??? ????.

???

? ? ?? ? 150mg? ??? ?? ??? 75mL? ??? ???? ???. ?? ?? ???????? ?? 0.1N ???????? ????. ???? ?? ?? ???? ???.

0.1N ?????? 1mL = 21.81mg C6H11NaO7

?????(Quinaldine red)?? : ?????(C21H23IN2 : 430.33) 100mg? ???? ?? 100mL? ??.

??

Sodium gluconate is the organic sodium salt of gluconic acid. Sodium gluconate is a chelator that forms stable complexes with various ions and ultimately prevents these ions from engaging in chemical reactions. Gluconates are naturally occurring substances that freely dissociate to the gluconate anion and its respective cations. Being fully biodegradable and non-toxic, it represents an environment friendly alternative to the common chelating agents used in cosmetics such as EDTA. In addition to this, sodium gluconate has a low acute toxicity to aquatic organisms.

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Sodium gluconate is a white to tan, granular to fine, practically odourless crystalline powder. It is very soluble in water, sparingly soluble in alcohol and insoluble in ether.

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Sodium gluconate is used as a natural preservative. It prevents the growth of microbes in our products to keep them safe for our consumers. It also works as a skin-conditioning agent and a chelating agent which helps cleansing products to foam better in hard water. You can often find sodium gluconate in soap, sunscreen, shampoo, toothpaste, hair products, makeup, and a variety of other personal care products.
Sodium gluconate has been used as a component of recording buffer used in two-electrode voltage-clamp (TEVC) recording in Xenopus laevis oocytes. It has also been used as a control for sodium.

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Research indicated that the addition of sodium gluconate significantly inhibited the reaction of geopolymers paste setting time of the geopolymer. An increase in sodium gluconate dosage from 0% to 3% significantly delays the initial setting time of geopolymer pastes from 31 min to 183 min. Microstructural analyses demonstrate that sodium gluconate interferes with the dissolution of precursor materials and the growth of the hydration gel in geopolymer, leading to an inhibitory effect on the early hardening process[1].

??

ChEBI: Sodium gluconate is an organic sodium salt having D-gluconate as the counterion. It has a role as a chelator. It contains a D-gluconate.

Safety Profile

Low toxicity by intravenous route. When heated to decomposition it emits acrid smoke and irritating fumes

Purification Methods

Crystallise it from a small volume of H2O (solubility is 59g/100mL at 25o), or dissolve it in H2O and add EtOH since it is sparingly soluble in EtOH. It is insoluble in Et2O. It forms a Cu complex in alkaline solution and a complex with Fe in neutral solution. [cf p 639, Sawyer & Bagger J Am Chem Soc 81 5302 1959, Beilstein 3 I 188.]

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