ChemicalBook >?? ???? >???3-(????)-4-??-4H-??-2,5-

???3-(????)-4-??-4H-??-2,5-

???3-(????)-4-??-4H-??-2,5- ??? ???

?? ??:: 1246616-66-9

???:: ???3-(????)-4-??-4H-??-2,5-

???(??):: ???3-(????)-4-??-4H-??-2,5-

???:: diMethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-

???(??):: Dimethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-dicarboxylate;Dolutegravir DL4B;Dolutegravir Intermediate3;diMethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-;Dimethyl 4-oxo-3-benzyloxy-4H-pyran-2,5-dicarboxyl;imethyl3-(benzyloxy)-4-oxo-4H-pyran-2,5-dicarboxylate;TIANFUCHEM diMethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-;2,5-Dimethyl 4-oxo-3-(phenylmethoxy)-4H-pyran-2,5-dicarboxylate;4-Oxo-3-benzyloxy-4H-pyran-2,5-dicarboxylic acid dimethyl ester;4-Oxo-3-(phenylMethoxy)-4H-pyran-2,5-dicarboxylic acid 2,5-diMethyl ester

CBNumber:: CB92685293

???:: C16H14O7

??? ??:: 318.28

MOL ??:: 1246616-66-9.mol

?? ?? 123

???3-(????)-4-??-4H-??-2,5- ??

?? ?: 534.9±50.0 °C(Predicted)

??: 1.34±0.1 g/cm3(Predicted)

?? ??: Sealed in dry,Room Temperature

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

???3-(????)-4-??-4H-??-2,5- C??? ??, ??, ??

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Dimethyl 3-(benzyloxy)-4-oxo-4H-pyran-2,5-dicarboxylate is a useful intermediate for the preparation of dolutegravir and dolutegravir salts used in antiretroviral medications.

???3-(????)-4-??-4H-??-2,5- ?? ?? ? ???

???

????????? Butanoic acid, 2-[(dimethylamino)methylene]-3-oxo-4-(phenylmethoxy)-, methyl ester ??? ???-t-????

?? ??

(4R,12aS)-N-(2,4-difluorobenzyl)-7-benzylhydroxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxaMide

???3-(????)-4-??-4H-??-2,5- ?? ??

???( 123)?? ??

???	??	???	??	?? ?	??
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???3-(????)-4-??-4H-??-2,5- ?? ??:

GSK1349572 (4R,12aS)-N-(2,4-difluorobenzyl)-7-benzylhydroxy-4-Methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxaMide Methyl 5-[[[(2,4-difluorophenyl)methyl]amino]carbonyl]-1-(2-oxoethyl)-4-oxo-3-[(phenylmethyl)oxy]-1,4-dihydro-2-pyridinecarboxylate

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