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BERGAPTOL

BERGAPTOL ??? ???
?? ??:
486-60-2
???:
BERGAPTOL
???(??):
4-HYDROXYPSORALEN;4-hydroxy-7H-furo[3,2-g]chroMen-7-one;BERGAPTOL;NSC 341958;Bergaptolc;BERGAPTOL hplc;5-HYDROXYPSORALEN;4-Hydroxybergapten;BERGAPTOL WITH HPLC;5-Hydroxyfuranocoumarin
CBNumber:
CB9340774
???:
C11H6O4
??? ??:
202.16
MOL ??:
486-60-2.mol

BERGAPTOL ??

???
287-290°C
?? ?
311.9±11.0 °C(Predicted)
??
1.526±0.06 g/cm3(Predicted)
?? ??
Sealed in dry,2-8°C
???
DMSO(?? ???), ???(?? ???)
?? ?? (pKa)
6.80±0.20(Predicted)
??? ??
Solid
??
??????? ???????
BRN
190104
LogP
1.405 (est)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 22-36
????? 22-24/25-26
WGK ?? 3
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H302 ??? ??? ?? ?? ?? - ?? ?? 4 ?? P264, P270, P301+P312, P330, P501
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
??????:
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P280 ????/???/???/?????? ?????.
P301+P312 ??? ???? ??? ????(??)? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.

BERGAPTOL C??? ??, ??, ??

??

A hydroxylated psoralen that acts as a potent inhibitors of debenzylation activity of CYP3A4 enzyme with an IC50 value of 24.92 and 42.93 μM, respectively. Recent studies suggest that it may have antiproliferative and anticancer properties.

BERGAPTOL ?? ?? ? ???

???

?? ??


BERGAPTOL ?? ??

???( 178)?? ??
??? ?? ??? ?? ?? ? ??
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BERGAPTOL ?? ??:

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