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1-????????

1-????????
1-???????? ??? ???
?? ??:
82-45-1
???:
1-????????
???(??):
1-????????;1-??????????;9,10-???????, 1-???;?????, 1-???-;??-????????;??-????????
???:
1-Aminoanthraquinone
???(??):
1-AMINOANTHRAQUINONE;1-aminoanthracene-9,10-dione;1AAQ;CI 37275;Fast Red AL;diazofastredal;Smoke Orange G;Diazo Fast Red AL;1-Aminoanthrachinon;1-AMINOANTHRAQUIONE
CBNumber:
CB9435391
???:
C14H9NO2
??? ??:
223.23
MOL ??:
82-45-1.mol
MSDS ??:
SDS

1-???????? ??

???
253-255 °C (lit.)
?? ?
364.52°C (rough estimate)
??
1.1814 (rough estimate)
???
1.4700 (estimate)
?? ??
room temp
???
???, ??, ?????, ???, ???, HCl? ???
?? ?? (pKa)
-0.51±0.20(Predicted)
??? ??
powder to crystal
?? ?? ??
37275
??
Orange to Brown to Dark red
???
312.5ug/L(25℃)
Merck
14,417
BRN
396360
Henry's Law Constant
2.0×103 mol/(m3Pa) at 25℃, Duchowicz et al. (2020)
???
????. ?, ? ???, ? ???, ????????, ????? ???? ????.
?? ??
?? ?? ??
???
???
InChI
1S/C14H9NO2/c15-11-7-3-6-10-12(11)14(17)9-5-2-1-4-8(9)13(10)16/h1-7H,15H2
InChIKey
KHUFHLFHOQVFGB-UHFFFAOYSA-N
SMILES
Nc1cccc2C(=O)c3ccccc3C(=O)c12
CAS ??????
82-45-1(CAS DataBase Reference)
NIST
1-Aminoanthraquinone(82-45-1)
EPA
1-Aminoanthraquinone (82-45-1)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
?? ???? ?? 36/37/38
????? 24/25
????(UN No.) 3077
WGK ?? 1
RTECS ?? CB5075000
TSCA TSCA listed
?? ?? 9
???? III
HS ?? 29223900
???? ??? 11 - Combustible Solids
???? ?? KE-01176
????(GHS): Health Hazard (GHS08)Environment (GHS09)Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H320 ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2B ?? P264, P305+P351+P338,P337+P313
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
H373 ??? ?? ?? ???? ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ?? ?? ???? ?? - ?? ?? ?? 2 ?? P260, P314, P501
H410 ??? ??? ?? ????? ?? ??? ?? ????? ?? - ?? ?? 1 ?? P273, P391, P501
??????:
P260 ??·?·??·???·??·...·????? ???? ???.
P261 ??·?·??·???·??·...·????? ??? ????.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P273 ???? ???? ???.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P314 ???? ??? ???? ??·??? ????.
P391 ???? ????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
1
1

1-???????? MSDS


C.I. 37275

1-???????? C??? ??, ??, ??

??? ??

deep brown crystalline powder. Soluble in hot nitrobenzene, toluene, xylene, ether, acetic acid, chloroform, benzene, slightly soluble in cold ethanol, insoluble in water.

??

1-Aminoanthraquinone is the most important intermediate for manufacturing acid, reactive, disperse, and vat dyes.

?? ??

1-Aminoanthraquinone has the ability to increase the solubility of anthraquinone derivatives in supercritical carbon dioxide. It is widely used in the preparation of various anthraquinone dyes. It also bridges Pt nanoparticles on carbon nanotubes as efficient electrocatalysts.

?? ??

1-Aminoanthraquinone (1-AAQ) is synthesized by the condensation of 2-substituted benzoic acid and xylene to yield 2-substituted-dimethylbenzophenone, subsequent oxidation of the methyl groups, ring closure to form a 1-substituted anthraquinone carboxylic acid, replacement of the 1-substituent with ammonia, and decarboxylation.

???

Toxicity studies showed histopathological changes in the kidneys and spleen, loss of breastfeeding behaviour, decreased pup survival on day 4 after birth, repeated doses and reproductive toxicity less than 40 mg/kg/day (lowest tested dose) of NOAEL. No adverse effects on reproductive parameters or teratogenicity were observed. caused excitability, weight loss, and liver and kidney changes in an inhalation study in rats; orthocytotic anaemia, weight loss, and organ changes (liver, spleen and heart) in a 2-week oral study in guinea pigs; and was not irritating to the skin or eyes of rabbits.

Safety Profile

Moderately toxic by intraperitoneal route. An eye irritant. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits toxic NO,. See also AMINES

Synthesis

Anthraquinone is sulfonated with nicotinic sulfuric acid in the presence of a small amount of mercury salt to generate anthraquinone-1-sulfonic acid, which is then neutralized with potassium hydroxide to form anthraquinone sulfonic acid potassium salt. Under high temperature and high pressure, ammonia and anthraquinone sulfonic acid potassium The salt action generates 1-aminoanthraquinone, and the generated sulfite reacts with the product again and the quality of the product decreases. Therefore, nitrobenzene sulfonate is usually used as an oxidant to oxidize sulfite to sulfate, which itself is reduced to m-aminobenzenesulfonic acid.

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???( 384)?? ??
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