ChemicalBook >?? ???? >(S)-4-N-Boc-2-??????
(S)-4-N-Boc-2-??????
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(S)-4-N-Boc-2-?????? ??
- ???
- 40-45 °C
- ??
- -16 º (c=1 in dioxane)
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- 268.7±15.0 °C(Predicted)
- ??
- 0.997±0.06 g/cm3(Predicted)
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- Keep in dark place,Inert atmosphere,2-8°C
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- ?? ?? (pKa)
- 8.52±0.40(Predicted)
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- ???? ?????
- ??? (Optical Rotation)
- [α]/D -16±2°, c = 1 in dioxane
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- Air Sensitive
- InChI
- InChI=1S/C10H20N2O2/c1-8-7-12(6-5-11-8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1
- InChIKey
- FMLPQHJYUZTHQS-QMMMGPOBSA-N
- SMILES
- N1(C(OC(C)(C)C)=O)CCN[C@@H](C)C1
- CAS ??????
- 147081-29-6(CAS DataBase Reference)
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- ?? ? ???? ?? (GHS)
| ??? ?? | Xi | ||
|---|---|---|---|
| ?? ???? ?? | 37/38-41-34 | ||
| ????? | 26-39-45-36/37/39 | ||
| ????(UN No.) | 3259 | ||
| WGK ?? | 3 | ||
| F ?????? | 10-34 | ||
| HS ?? | 29335990 | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
(S)-4-N-Boc-2-?????? C??? ??, ??, ??
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(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. This compound also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.??? ??
colorless to yellow liquid??
Laboratory chemicals, Manufacture of substances.(S)-4-N-Boc-2-?????? ?? ?? ? ???
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(S)-4-N-Boc-2-?????? ?? ??
???( 360)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 |
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| Shanghai UCHEM Inc. | +862156762820 +86-13564624040 |
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| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20122 | 58 |
| Hefei Lbao Physical & Chemical Science Co.,Ltd | +15184799099 |
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| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 |
sales@capot.com | China | 29640 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 |
info@dakenam.com | China | 14014 | 58 |
(S)-4-N-Boc-2-?????? ?? ??:
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