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2-??????????

2-??????????
2-?????????? ??? ???
?? ??:
3958-60-9
???:
2-??????????
???(??):
2-??????????
???:
2-Nitrobenzyl bromide
???(??):
1-(Bromomethyl)-2-nitrobenzene;2-Nitrobenzyl;LIXI-011;2-Benzyl bromide;o-Nitrobenaylbromide;2-Nitrobenzyl bromid;-Bromo-2-mitrotoluene;2-NITROBENZYL BROMIDE;2-Nitrobenayl broMide;O-NITROBENZYL BROMIDE
CBNumber:
CB9478950
???:
C7H6BrNO2
??? ??:
216.03
MOL ??:
3958-60-9.mol
MSDS ??:
SDS

2-?????????? ??

???
44-46 °C (lit.)
?? ?
265.51°C (rough estimate)
??
1.6841 (rough estimate)
???
1.6120 (estimate)
???
>230 °F
?? ??
Inert atmosphere,2-8°C
???
?????(?? ???), DMSO(?? ???), ???????(?? ???)
??? ??
?? ?? ??? ??
??
????? ?? ????
???
???
BRN
638991
???
???
InChI
InChI=1S/C7H6BrNO2/c8-5-6-3-1-2-4-7(6)9(10)11/h1-4H,5H2
InChIKey
HXBMIQJOSHZCFX-UHFFFAOYSA-N
SMILES
C1(CBr)=CC=CC=C1[N+]([O-])=O
CAS ??????
3958-60-9(CAS DataBase Reference)
NIST
2-Nitrobenzyl bromide(3958-60-9)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? C
?? ???? ?? 34
????? 26-36/37/39-45
????(UN No.) UN 3261 8/PG 2
WGK ?? 3
F ?????? 4.8-19-21
?? ?? 8
???? II
HS ?? 29049085
???? ??? 8A - Combustible corrosive hazardous materials
Hazard Classifications Eye Dam. 1
Skin Corr. 1B
????(GHS): Corrosion (GHS05)Exclamation Mark (GHS07)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H314 ??? ?? ??? ?? ??? ??? ????? ?? ????? ?? 1A, B, C ?? P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P260 ??·?·??·???·??·...·????? ???? ???.
P280 ????/???/???/?????? ?????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
NFPA 704
1
3 0

2-?????????? MSDS


2-Nitrobenzyl bromide

2-?????????? C??? ??, ??, ??

??? ??

white to light yellow crystal powde

??

2-Nitrobenzyl bromide is used in the preparation of S-2-nitrobenzyl-cysteine by reaction with L-cysteine. It is also used for the introduction of the 2-nitrobenzyl protecting group in organic synthesis. It plays an important role in the production of expectorant agent. Further, it is employed for caging unprotected cysteine-containing or thiophosphorylated peptides in aqueous solution. In addition to this, it is used in the preparation of (R)- and (S)-3-amino-3,4-dihydro-1H-quinolin-2-one.

Biochem/physiol Actions

2-Nitrobenzyl bromide reacts with L-cysteine to form S-2-nitrobenzyl-cysteine which was used for modification of ultra-low-gelling-temperature (ULGT) agarose.

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