???????????
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??????????? ??
- ???
- 121-124°C
- ?? ??
- -20°C
- ???
- H2O: ≥50mg/mL, ??, ?? ~ ??? ???
- ??? ??
- Solid
- ??
- White to off-white
- ???? ??
- synthetic (organic)
- ???
- water: soluble 50mg/mL, clear, colorless to light yellow
- InChI
- InChI=1S/C11H10O5S.Na.H/c1-11(17(14,15)16)6-9(12)7-4-2-3-5-8(7)10(11)13;;/h2-5H,6H2,1H3,(H,14,15,16);;
- InChIKey
- JWNUEPMMANLFQO-UHFFFAOYSA-N
- SMILES
- O=C1C(CC(=O)C2=CC=CC=C12)(C)S(O)(=O)=O.[NaH]
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi,N | ||
|---|---|---|---|
| ?? ???? ?? | 36-50/53-36/38 | ||
| ????? | 26-61-60-24/25 | ||
| ????(UN No.) | UN 3077 9 / PGIII | ||
| WGK ?? | 3 | ||
| TSCA | TSCA listed | ||
| ???? ??? | 11 - Combustible Solids | ||
| Hazard Classifications | Aquatic Acute 1 Aquatic Chronic 1 Eye Irrit. 2 Skin Irrit. 2 |
| ????(GHS): |
 
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| ?? ?: | Warning | ||||||||||||||||||||||||||||
| ??·?? ??: |
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Menadione sodium bisulfite (MSB, also known as vitamin K3), is a crucial growth regulator mediating plant defense response. This substance is used clinically in China to treat hemorrhagic diseases caused by vitamin K deficiency and globally as a vitamin K supplement. This compound and its complex (MSBC) are water-soluble compounds. Menadione and the menadione sodium bisulfite complex are the sources of vitamin K activity in commercial laboratory rodent diets. Menadione possesses high biological activity, but its absorption depends on the amount of fat in the diet. Compared with Menadione, the menadione sodium bisulfite complex is more readily absorbed and is almost as active on a molar basis as phylloquinone. XTT, a tetrazolium salt, could converted to formazan in the presence of an electron coupling reagent such as menadione sodium bisulfite. The formed formazan does not need to be solubilized. Hence, the XTT test, a cytotoxicity evaluation method, is quicker and safer compared with MTT[1-2].??? ??
white powder??
Menadione sodium bisulfite has been used:- as a priming agent in tomato for improving salt tolerance
- to induce reactive oxygen species (ROS) in human lung epithelium BEAS-2B microtissues
- to induce endogenous superoxide production in mouse C17.2 neural stem cells
??
ChEBI: An organic sodium salt that is the monosodium salt of menadione sulfonate. A synthetic naphthoquinone without the isoprenoid side chain and biological activity, but can be converted to active vitamin K2, menaquinone, after alkylation i vivo.???
Inflammation of the walls of a veinFacial flushing
Cardiovascular collapse
Severe shock-like reactions
Sweating Injection site reactions
Chest constriction
Pain
Shortness of breath
Bluish discoloration of the skin
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???( 285)?? ??
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