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1,3-??[???(??????)?????]???

1,3-??[???(??????)?????]???
1,3-??[???(??????)?????]??? ??? ???
?? ??:
64431-96-5
???:
1,3-??[???(??????)?????]???
???(??):
1,3-??[???(??????)?????]???
???:
Bis-Tris propane
???(??):
B-T-Propane;1,3-BIS[TRIS(HYDROXYMETHYL)METHYLAMINO]PROPANE;yehebio;BIS-TRIS PROPANE;BIS-TRIS propane 99+%;BIS-Tris Propane, ULTROL;BIS-TRIS PROPANE SIGMAULTRA;1.0 M BIS-TRIS propane pH 8.5;1.0 M BIS-TRIS propane pH 6.6;1.0 M BIS-TRIS propane pH 8.4
CBNumber:
CB9769557
???:
C11H26N2O6
??? ??:
282.33
MOL ??:
64431-96-5.mol
MSDS ??:
SDS

1,3-??[???(??????)?????]??? ??

???
164-165 °C(lit.)
?? ?
573.3±50.0 °C(Predicted)
??
1.326±0.06 g/cm3(Predicted)
?? ??
room temp
???
H2O: 1 M at 20 °C, ??, ??
??? ??
??/??
??
???
pH ??
6.3 - 9.5
??????(pH)
9.0-10.1 (20-25℃, 1M in water)
?? ?? (pKa)
(1) 6.8, (2) 9.0(at 25℃)
???? ??
synthetic
???
?? ?????.
BRN
1786109
?? ??
?? ?? ??
InChI
InChI=1S/C11H26N2O6/c14-4-10(5-15,6-16)12-2-1-3-13-11(7-17,8-18)9-19/h12-19H,1-9H2
InChIKey
HHKZCCWKTZRCCL-UHFFFAOYSA-N
SMILES
C(NC(CO)(CO)CO)CCNC(CO)(CO)CO
CAS ??????
64431-96-5(CAS DataBase Reference)
Absorption
≤0.05 at 290 at 30% (w/w)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xn
?? ???? ?? 20/21/22-36/37/38
????? 22-24/25-26-36
WGK ?? 3
HS ?? 29221980
???? ??? 11 - Combustible Solids
????(GHS): Exclamation Mark (GHS07)
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ??
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
NFPA 704
1
1 1

1,3-??[???(??????)?????]??? C??? ??, ??, ??

??

BIS-TRIS Propane is Good′s buffer. It acts as ligand and forms series of dinuclear hydroxo complexes with Lanthanides(III) in the pH range 7-9. It is useful for diagnostic assay manufacturing industry.

??? ??

White powder

??

BIS-Tris Propane is a buffer that is useful in the pH 6.3 - 9.5 range. This wide buffering range is due to its two pKa values, 6.8 (pKa1) and 9.0 (pKa2), being so close. Because of the wide buffering range, particularly down to pH 6 - 7, this buffer has been used to enhance the stability or activity of restriction enzymes, compared to Tris buffer (which is a poor buffer below pH 7.5 and has a comparatively large change in pKa with temperature).

?? ??

This trihydroxyamine analog, also known as bis-tris propane, presents as a white to almost white crystalline powder. Store in a cool and dark place. 1,3-Bis[tris(hydroxymethyl)methylamino]propane is known to be incompatible with oxidizing agents and should not be handled in their vicinity.

1,3-??[???(??????)?????]??? ?? ?? ? ???

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1,3-??[???(??????)?????]??? ?? ??

???( 460)?? ??
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1,3-??[???(??????)?????]??? ?? ??:

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