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??????(2-)

??????(2-)
??????(2-) ??? ???
?? ??:
75-29-6
???:
??????(2-)
???(??):
2-???????;?????????;??????(2-);?????????;??????????
???:
2-Chloropropane
???(??):
ISOPROPYL CHLORIDE;2-CHLOROPROP-1-ENE;2-CHLORO-1-PROPENE;2-chloropropane(isopropylchloride);R280da;Isoprid;Narcosop;iso-C3H7Cl;2-Chlorpropan;2-CHLOROPROPANE
CBNumber:
CB9854220
???:
C3H7Cl
??? ??:
78.54
MOL ??:
75-29-6.mol
MSDS ??:
SDS

??????(2-) ??

???
-118 °C
?? ?
35 °C
??
0.859 g/mL at 25 °C(lit.)
???
28.11 psi ( 55 °C)
???
n20/D 1.395(lit.)
???
−31 °F
?? ??
Store below +30°C.
???
???: ???(lit.)
??? ??
??? ??
??
??~???
????
2.8-10.7%(V)
???
3.1g/L(20℃)
Merck
14,5211
BRN
1730782
Henry's Law Constant
5.7×10-4 mol/(m3Pa) at 25℃, Brockbank (2013)
???
????. ?? ???, ?? ??? ???? ????. ???? ??? ???? ????. ???? ?? 0C? ?????.
InChI
1S/C3H7Cl/c1-3(2)4/h3H,1-2H3
InChIKey
ULYZAYCEDJDHCC-UHFFFAOYSA-N
SMILES
CC(C)Cl
CAS ??????
75-29-6(CAS DataBase Reference)
NIST
Propane, 2-chloro-(75-29-6)
EPA
2-Chloropropane (75-29-6)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? F+,Xi,Xn,F
?? ???? ?? 12-36/37-20/21/22-11-40
????? 9-29-36-26-16
????(UN No.) UN 2356
WGK ?? 3
RTECS ?? UC7200000
F ?????? 10-23
?? ?? ?? 590 °C
TSCA TSCA listed
?? ?? 3
???? I
HS ?? 29031980
???? ??? 3 - Flammable liquids
Hazard Classifications Acute Tox. 4 Dermal
Acute Tox. 4 Inhalation
Acute Tox. 4 Oral
Flam. Liq. 2
?? ?? ??? 75-29-6(Hazardous Substances Data)
?? LD50 orally in Rabbit: > 2000 mg/kg LD50 dermal Rabbit > 2000 mg/kg
???? ?? KE-05871
????(GHS): Flame (GHS02)Exclamation Mark (GHS07)Health Hazard (GHS08)
?? ?: Danger
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H225 ???? ?? ? ?? ??? ?? ?? 2 ?? P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H303 ??? ??? ? ?? ?? ?? ?? - ?? ?? 5 P312
H305 ??? ??? ???? ??? ? ?? ?? ????? ?? 2 ?? P301+P310, P331, P405, P501
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? P264, P280, P305+P351+P338,P337+P313P
H336 ?? ?? ???? ??? ? ?? ?????? ?? ??(1? ??);???? ?? 3 ?? P261, P271, P304+P340, P312,P403+P233, P405, P501
H371 ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ??(????? ?? ???? ??? ???? ???? ???? ????? ??? ????? ??) ?? ???? ?? - 2? ?? ?? 2 ?? P260, P264, P270, P309+P311, P405,P501
H373 ??? ?? ?? ???? ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ?? ?? ???? ?? - ?? ?? ?? 2 ?? P260, P314, P501
??????:
P210 ?·???·??·????? ????? - ?? ???.
P233 ??? ??? ?????. ??? ??? ? ?? ?? ??? ???? ?????.
P240 ??? ????? ?? ? ??????.
P241 ?? ??? ??[???/??/??/...]?(?) ?????.
P242 ???? ???? ?? ??? ?????
P243 ??? ?? ??? ????.
P260 ??·?·??·???·??·...·????? ???? ???.
P264 ?? ??? ?? ??? ????.
P264 ?? ??? ?? ??? ????.
P270 ? ??? ??? ??? ???, ???? ???? ???.
P271 ?? ?? ??? ? ?? ???? ?????.
P280 ????/???/???/?????? ?????.
P301+P310 ???? ?? ????(??)? ??? ????.
P303+P361+P353 ??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P331 ??? ?? ???.
P332+P313 ?? ??? ??? ???? ??· ??? ????.
P337+P313 ?? ?? ??? ???? ???? ??· ??? ????.
P370+P378 ?? ? ?? ?? ?? (Section 5. ??, ??? ????? ??? ???)?(?) ?????.
P403+P233 ??? ??? ? ?? ?? ??? ???? ?????.
P403+P235 ??? ? ?? ?? ???? ???? ?????.
P405 ???? ?????.
P501 ...? ??? / ??? ?? ???.
NFPA 704
4
2 0

??????(2-) MSDS


2-Chloropropane

??????(2-) C??? ??, ??, ??

??? ??

Colourless liquid

??

2-Chloropropane decomposes by first-order reaction to give hydrogen chloride and propylene. It is a short-chain chlorinated paraffins that is a component in lubricant additives, metal processing, leather fat-liquoring, plastics softening, PVC plasticizing, flame retardants in paints, adhesives and sealants. It shows anesthetic properties. Further, it is used as an alternative foam-blowing agent.
2-Chloropropane is used as a solvent and an intermediate.It can be used as a reactant:
In the Friedel-Crafts alkylation reaction of difluorobenzene and toluene using solid acid and methylalumoxane catalysts, respectively.
To prepare 4-amino-3-iodo-1-(isopropyl)pyrazolo[3,4-d]pyrimidine, a key intermediate for the synthesis of PfPK7 kinase inhibitors.
It is used to prepare benzylisopropylphenylphosphine and chlorodiethylisopropylsilane.

?? ??

A colorless liquid with a chloroform-like odor. Vapors heavier than air. Less dense than water. May irritate skin and eyes, and be narcotic in high concentrations. A fire and explosion risk. Used to make other chemicals.

??? ?? ??

Highly flammable. Slightly soluble in water.

?? ???

Halogenated aliphatic compounds, such as 2-Chloropropane, are moderately or very reactive. Reactivity generally decreases with increased degree of substitution of halogen for hydrogen atoms. Low molecular weight haloalkanes are highly flammable and can react with some metals to form dangerous products. Materials in this group are incompatible with strong oxidizing and reducing agents. Also, they are incompatible with many amines, nitrides, azo/diazo compounds, alkali metals, and epoxides.

???

Highly flammable, fire and explosion risk, explosive limits in air 2.8–10.7%.

????

ACUTE/CHRONIC HAZARDS: Fire hazard: Highly dangerous; when exposed to heat, flame or oxidizers. Explosion hazard: Moderate when exposed to heat or flame.

????

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety Profile

Mutation data reported. A flammable liquid. A very dangerous fire hazard when exposed to heat, flame, or oxidners. When heated to decomposition it emits toxic fumes of Cl-. See also 1 CHLOROPROPANE.

Purification Methods

Purify the chloride with 95% H2SO4 as described for isopropyl bromide, then dry with MgSO4, P2O5 or CaH2, and fractionally distil it from Na2CO3 or CaH2. Alternatively, a stream of oxygen containing ca 5% ozone is passed through the chloride for about three times as long as is necessary to obtain the first coloration of starch iodide paper by the exit gas, and the liquid is then washed with NaHCO3 solution to hydrolyse ozonides and remove organic acids before drying and distilling. [Beilstein 1 IV 191.]

??????(2-) ?? ?? ? ???

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??????(2-) ?? ??:

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